SCHEMBL1325155

SCHEMBL1325155

CN[C@@H](Cc1ccc(I)cc1)C(=O)O

nearest known ligand 0.54

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
FPR2 P25090 4/20 0.54
CYP1A2 P05177 1/20 0.44
CYP2D6 P10635 1/20 0.44
ACE P12821 5/20 0.44
MME P08473 5/20 0.44
ACE2 Q9BYF1 5/20 0.44
CPA1 P15085 3/20 0.44
ALB P02768 1/20 0.44
IL2 P60568 1/20 0.44
FOLH1 Q04609 1/20 0.44
APEX1 P27695 1/20 0.43
PMP22 Q01453 1/20 0.43
PPARG P37231 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1325154 1.00 FPR2 (0.54) FPR2CYP1A2CYP2D6ACEMME
Hydrochloric Acid SCHEMBL2521612 0.98 FPR2 (0.52) FPR2CYP1A2CYP2D6ACEMME
SCHEMBL24311640 0.86 CYP1A2 (0.44) FPR2CYP1A2CYP2D6ALBIL2
SCHEMBL24311576 0.86 CYP1A2 (0.44) FPR2CYP1A2CYP2D6ALBIL2
SCHEMBL8717678 0.84 FPR2 (0.46) FPR2CYP1A2CYP2D6APEX1PMP22
SCHEMBL14037245 0.84 FPR2 (0.46) FPR2CYP1A2CYP2D6APEX1PMP22
SCHEMBL161943 0.84 FOLH1 (0.60) ACEMMEACE2CPA1FOLH1
SCHEMBL8693619 0.84 FPR2 (0.55) FPR2CYP1A2CYP2D6ACEMME
SCHEMBL8745399 0.84 FPR2 (0.55) FPR2CYP1A2CYP2D6ACEMME
SCHEMBL160418 0.84 FOLH1 (0.60) ACEMMEACE2CPA1FOLH1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 31 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-122028793-A Fungicidal compositions 先正达农作物保护股份公司 2026-05-12 CN claimed
CN-118265452-A Fungicidal compositions 先正达农作物保护股份公司 2024-06-28 CN claimed
CN-115697056-A Fungicidal compositions 先正达农作物保护股份公司 2023-02-03 CN claimed
CN-115697055-A Fungicidal compositions 先正达农作物保护股份公司 2023-02-03 CN claimed
CN-115666239-A Fungicidal compositions 先正达农作物保护股份公司 2023-01-31 CN claimed
CN-115666240-A Fungicidal compositions 先正达农作物保护股份公司 2023-01-31 CN claimed
CN-115666241-A Fungicidal compositions 先正达农作物保护股份公司 2023-01-31 CN claimed
CN-115666238-A Fungicidal compositions 先正达农作物保护股份公司 2023-01-31 CN claimed
CN-122028793-A Fungicidal compositions 先正达农作物保护股份公司 2026-05-12 CN disclosed
US-12371454-B2 Cyclic peptide compound having Kras inhibitory action CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) 2025-07-29 US disclosed
US-20240400617-A1 CYCLIC PEPTIDE COMPOUND HAVING KRAS INHIBITORY ACTION CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) 2024-12-05 US disclosed
CN-118265452-A Fungicidal compositions 先正达农作物保护股份公司 2024-06-28 CN disclosed
US-20240148821-A1 PHARMACEUTICAL USE OF CYCLIC PEPTIDE COMPOUND CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) 2024-05-09 US disclosed
EP-4316503-A1 PHARMACEUTICAL USE OF CYCLIC PEPTIDE COMPOUND CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) 2024-02-07 EP disclosed
US-20120122799-A1 CYCLIC PEPTIDE ANTITUMOR AGENTS NORTHWESTERN UNIVERSITY (US) 2012-05-17 US disclosed
US-8058244-B2 Cyclic peptide antitumor agents NORTHWESTERN UNIVERSITY (US) 2011-11-15 US disclosed
US-20100204088-A1 Cyclic Peptide Antitumor Agents SILVERMAN RICHARD B 2010-08-12 US disclosed
US-7709443-B2 For treatment of human melanoma, pancreatic, breast, prostate cancer cells NORTHWESTERN UNIVERSITY (US) 2010-05-04 US disclosed
US-20050159346-A1 Cyclic peptide antitumor agents NORTHWESTERN UNIVERSITY 2005-07-21 US disclosed
WO-2005034982-A1 CYCLIC PEPTIDE ANTITUMOR AGENTS NORTHWESTERN UNIVERSITY (US) 2005-04-21 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240400617-A1 CYCLIC PEPTIDE COMPOUND HAVING KRAS INHIBITORY ACTION KRAS, NRAS, HRAS FPR2 1502/4885CYP1A2 4845/4885CYP2D6 4576/4885
US-20100204088-A1 Cyclic Peptide Antitumor Agents VIP, IAPP, NGLY1 FPR2 1498/4885CYP1A2 4882/4885CYP2D6 4842/4885
US-20120122799-A1 CYCLIC PEPTIDE ANTITUMOR AGENTS VIP, IAPP, NGLY1 FPR2 1498/4885CYP1A2 4882/4885CYP2D6 4842/4885
US-20240148821-A1 PHARMACEUTICAL USE OF CYCLIC PEPTIDE COMPOUND VIP, IAPP, KRAS FPR2 541/4885CYP1A2 4648/4885CYP2D6 2906/4885
US-12371454-B2 Cyclic peptide compound having Kras inhibitory action KRAS, NRAS, HRAS FPR2 1502/4885CYP1A2 4845/4885CYP2D6 4576/4885
US-20050159346-A1 Cyclic peptide antitumor agents VIP, IAPP, NGLY1 FPR2 1498/4885CYP1A2 4882/4885CYP2D6 4842/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.