Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM5A | P29375 | 1/20 | 0.32 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.31 |
| ▸ | VNN1 | O95497 | 1/20 | 0.31 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.30 |
| ▸ | PROKR1 | Q8TCW9 | 1/20 | 0.30 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3063519 | 1.00 | KDM5A (0.32) | KDM5ATRPV1VNN1IRAK4PROKR1 | |
| SCHEMBL3063280 | 1.00 | KDM5A (0.32) | KDM5ATRPV1VNN1IRAK4PROKR1 | |
| SCHEMBL3063282 | 1.00 | KDM5A (0.32) | KDM5ATRPV1VNN1IRAK4PROKR1 | |
| SCHEMBL3063521 | 1.00 | KDM5A (0.32) | KDM5ATRPV1VNN1IRAK4PROKR1 | |
| SCHEMBL3063288 | 1.00 | KDM5A (0.32) | KDM5ATRPV1VNN1IRAK4PROKR1 | |
| SCHEMBL3071272 | 0.89 | SCD5 (0.32) | KDM5ATRPV1VNN1IRAK4PROKR1 | |
| SCHEMBL3074619 | 0.89 | SCD5 (0.32) | KDM5ATRPV1VNN1IRAK4PROKR1 | |
| SCHEMBL3074617 | 0.89 | SCD5 (0.32) | KDM5ATRPV1VNN1IRAK4PROKR1 | |
| SCHEMBL3071276 | 0.89 | SCD5 (0.32) | KDM5ATRPV1VNN1IRAK4PROKR1 | |
| SCHEMBL3071271 | 0.89 | SCD5 (0.32) | KDM5ATRPV1VNN1IRAK4PROKR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010091411-A1 | PIPERIDINYL CYCLIC AMIDO ANTIVIRAL AGENTS | GLAXOSMITHKLINE LLC (US) | 2010-08-12 | — | — | WO | disclosed |