Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADCY8 | P40145 | 1/20 | 0.45 |
| ▸ | ADCY1 | Q08828 | 1/20 | 0.45 |
| ▸ | HTR2A | P28223 | 1/20 | 0.43 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.41 |
| ▸ | POLQ | O75417 | 1/20 | 0.41 |
| ▸ | AR | P10275 | 3/20 | 0.38 |
| ▸ | ACMSD | Q8TDX5 | 2/20 | 0.38 |
| ▸ | BACE1 | P56817 | 1/20 | 0.37 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.36 |
| ▸ | KMO | O15229 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13256360 | 1.00 | ADCY8 (0.45) | ADCY8ADCY1HTR2APDK2POLQ | |
| SCHEMBL22246620 | 0.98 | HTR2A (0.44) | ADCY8ADCY1HTR2APDK2POLQ | |
| SCHEMBL12762087 | 0.95 | HTR2A (0.44) | ADCY8ADCY1HTR2APDK2POLQ | |
| SCHEMBL18162314 | 0.91 | POLQ (0.47) | ADCY8ADCY1HTR2APDK2POLQ | |
| SCHEMBL3434595 | 0.91 | POLQ (0.47) | ADCY8ADCY1HTR2APDK2POLQ | |
| SCHEMBL18162311 | 0.86 | POLQ (0.44) | ADCY8ADCY1HTR2APDK2POLQ | |
| SCHEMBL13256370 | 0.84 | HTR2A (0.48) | ADCY8ADCY1HTR2APDK2POLQ | |
| SCHEMBL30228726 | 0.83 | HTR2C (0.56) | HTR2A | |
| SCHEMBL25763098 | 0.82 | POLQ (0.39) | ADCY8ADCY1HTR2APDK2POLQ | |
| SCHEMBL25767649 | 0.81 | POLQ (0.41) | ADCY8ADCY1HTR2APDK2POLQ |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010088574-A1 | AZABENZIMIDAZOLES AND RELATED ANALOGS AS SIRTUIN MODULATORS | SIRTRIS PHARMACEUTICALS, INC. (US) | 2010-08-05 | — | — | WO | disclosed |