Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 | P21554 | 2/20 | 0.39 |
| ▸ | CNR2 | P34972 | 2/20 | 0.39 |
| ▸ | GBA1 | P04062 | 1/20 | 0.39 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.36 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.33 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.33 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.33 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.31 |
| ▸ | SLC6A9 | P48067 | 1/20 | 0.31 |
| ▸ | ACHE | P22303 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13015720 | 0.88 | GBA1 (0.45) | CNR1CNR2GBA1HSD11B1KDM4E | |
| SCHEMBL24926382 | 0.82 | HRH3 (0.34) | CNR1CNR2GBA1NR1H2CHRM5 | |
| SCHEMBL22852538 | 0.82 | HRH3 (0.34) | CNR1CNR2GBA1NR1H2CHRM5 | |
| SCHEMBL16254882 | 0.77 | GBA1 (0.41) | CNR1CNR2GBA1HSD11B1KDM4E | |
| SCHEMBL27126557 | 0.75 | GBA1 (0.40) | CNR1CNR2GBA1HSD11B1KDM4E | |
| SCHEMBL16253011 | 0.73 | CNR2 (0.44) | CNR1CNR2GBA1HSD11B1KDM4E | |
| SCHEMBL27282041 | 0.72 | L3MBTL1 (0.36) | SLC6A9 | |
| SCHEMBL12595521 | 0.72 | L3MBTL1 (0.36) | SLC6A9 | |
| SCHEMBL16480437 | 0.72 | KCNH2 (0.44) | CNR1CNR2GBA1HSD11B1 | |
| SCHEMBL25685818 | 0.72 | NR1H2 (0.36) | NR1H2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010096371-A2 | HETEROCYCLIC COMPOUNDS WHICH MODULATE THE CB2 RECEPTOR | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2010-08-26 | — | — | WO | disclosed |