Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 7/20 | 0.66 |
| ▸ | CYP3A4 | P08684 | 5/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.50 |
| ▸ | TSHR | P16473 | 4/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.50 |
| ▸ | CA1 | P00915 | 2/20 | 0.50 |
| ▸ | ATM | Q13315 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | TP53 | P04637 | 2/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | FAAH | O00519 | 1/20 | 0.42 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | USP2 | O75604 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1325938 | 1.00 | CA2 (0.66) | CA2CYP3A4ALDH1A1TSHRTDP1 | |
| SCHEMBL11483943 | 0.94 | CA2 (0.58) | CA2CYP3A4ALDH1A1TSHRTDP1 | |
| SCHEMBL8515069 | 0.94 | CA2 (0.62) | CA2CYP3A4ALDH1A1TSHRTDP1 | |
| SCHEMBL29048845 | 0.93 | CA2 (0.58) | CA2CYP3A4ALDH1A1TSHRTDP1 | |
| SCHEMBL26218280 | 0.92 | CA2 (0.56) | CA2CYP3A4ALDH1A1TSHRTDP1 | |
| SCHEMBL14836357 | 0.92 | CA2 (0.60) | CA2CYP3A4ALDH1A1TSHRTDP1 | |
| SCHEMBL28155829 | 0.91 | CA2 (0.53) | CA2CYP3A4ALDH1A1TSHRTDP1 | |
| SCHEMBL28212273 | 0.90 | CA2 (0.55) | CA2CYP3A4ALDH1A1TSHRTDP1 | |
| SCHEMBL13127898 | 0.90 | CA2 (0.58) | CA2CYP3A4ALDH1A1TSHRTDP1 | |
| SCHEMBL11663150 | 0.90 | CA2 (0.58) | CA2CYP3A4ALDH1A1TSHRTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 136 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117965890-A | Composite extraction system and application thereof in lithium ion extraction separation | 北京索特莱克科技发展有限公司 | 2024-05-03 | — | — | CN | claimed |
| CN-116239490-A | Amide extractant, preparation method and application thereof | 中国原子能科学研究院 | 2023-06-09 | — | — | CN | claimed |
| CN-114405060-B | Method for synchronously separating lithium, boron and magnesium in salt lake brine through three-liquid-phase extraction | 中国科学院过程工程研究所 | 2023-03-21 | — | — | CN | claimed |
| CN-115028545-A | Preparation method of phenol extracting agent DW503 in wastewater | 江苏万盛大伟化学有限公司 | 2022-09-09 | — | — | CN | claimed |
| CN-114405060-A | Method for synchronously separating lithium, boron and magnesium in salt lake brine through three-liquid-phase extraction | 中国科学院过程工程研究所 | 2022-04-29 | — | — | CN | claimed |
| CN-107441766-B | Extraction composition, extraction system and application thereof | 中国科学院上海有机化学研究所 | 2021-06-08 | — | — | CN | claimed |
| CN-107441765-B | Extraction composition, extraction system and application thereof | 中国科学院上海有机化学研究所 | 2021-04-20 | — | — | CN | claimed |
| CN-107441767-B | Extraction composition, extraction system and application thereof | 中国科学院上海有机化学研究所 | 2021-04-20 | — | — | CN | claimed |
| CN-107619950-B | Extraction composition, extraction system and application thereof | 中国科学院上海有机化学研究所 | 2021-04-20 | — | — | CN | claimed |
| CN-107441764-B | Extraction composition, extraction system and application thereof | 中国科学院上海有机化学研究所 | 2021-04-20 | — | — | CN | claimed |
| CN-107447108-A | A kind of extracts composition, extraction system, extracting process and back extraction method | 中国科学院上海有机化学研究所 | 2017-12-08 | — | — | CN | claimed |
| CN-107447117-A | A kind of extracts composition, extraction system, extracting process and back extraction method | 中国科学院上海有机化学研究所 | 2017-12-08 | — | — | CN | claimed |
| US-20110144033-A1 | Proteasome Inhibitors and Methods of Using the Same | CEPHALON, INC. (US) | 2011-06-16 | — | — | US | claimed |
| US-7915236-B2 | Proteasome inhibitors and methods of using the same | CEPHALON, INC. (US) | 2011-03-29 | — | — | US | claimed |
| EP-1660507-B9 | PROTEASOME INHIBITORS AND METHODS OF USING THE SAME | CEPHALON INC (US) | 2010-03-24 | — | — | EP | claimed |
| US-20090291918-A1 | PROTEASOME INHIBITORS AND METHODS OF USING THE SAME | CEPHALON, INC. (US) | 2009-11-26 | — | — | US | claimed |
| EP-1660507-B1 | PROTEASOME INHIBITORS AND METHODS OF USING THE SAME | CEPHALON INC (US) | 2009-08-05 | — | — | EP | claimed |
| EP-1660507-A2 | PROTEASOME INHIBITORS AND METHODS OF USING THE SAME | CEPHALON, INC. (US) | 2006-05-31 | — | — | EP | claimed |
| US-20050107307-A1 | Proteasome inhibitors and methods of using the same | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2005-05-19 | — | — | US | claimed |
| WO-2005021558-A2 | PROTEASOME INHIBITORS AND METHODS OF USING THE SAME | CEPHALON, INC. (US) | 2005-03-10 | — | — | WO | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090291918-A1 | PROTEASOME INHIBITORS AND METHODS OF USING THE SAME | PSMB11, PSMB5, PSMB6 | CA2 2765/4885CYP3A4 3988/4885ALDH1A1 3935/4885 |
| US-20050107307-A1 | Proteasome inhibitors and methods of using the same | PSMB11, PSMB5, PSMB6 | CA2 2765/4885CYP3A4 3988/4885ALDH1A1 3935/4885 |
| US-20110144033-A1 | Proteasome Inhibitors and Methods of Using the Same | PSMB11, PSMB5, PSMB6 | CA2 2765/4885CYP3A4 3988/4885ALDH1A1 3935/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.