SCHEMBL13263045

SCHEMBL13263045

CC/C=C/COc1ccc(-c2ccc(-c3ccc(C4OCC(C)CO4)cc3F)cc2)c(F)c1F

nearest known ligand 0.33

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
FPR2 P25090 5/20 0.33
KDM1A O60341 2/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8948476 0.88 HTR2C (0.36) FPR2
SCHEMBL13263063 0.88 KDM1A (0.32) FPR2KDM1A
SCHEMBL8949892 0.86 FPR2 (0.31) FPR2
SCHEMBL8952802 0.86 FPR2 (0.31) FPR2
SCHEMBL8951707 0.85 FPR2 (0.30) FPR2
SCHEMBL8945046 0.84 FPR2 (0.33) FPR2KDM1A
SCHEMBL8948572 0.82 HTR2C (0.35) FPR2KDM1A
SCHEMBL13000775 0.82 FPR2 (0.31) FPR2
SCHEMBL8950035 0.81 FPR2 (0.30) FPR2
SCHEMBL13000131 0.80 FPR2 (0.31) FPR2KDM1A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2206695-A1 TETRA- OR PENTA-CYCLIC LIQUID CRYSTALLINE COMPOUND HAVING LATERAL FLUORINE, LIQUID CRYSTAL COMPOSITION, AND LIQUID CRYSTAL DISPLAY ELEMENT Chisso Corporation (JP) 2010-07-14 EP disclosed