SCHEMBL13263282

SCHEMBL13263282

C/C=C/C1CCC(C2CCC(c3ccc(-c4ccc(-c5cccc(F)c5F)cc4)c(F)c3)CC2)CC1

nearest known ligand 0.35

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
CYP3A4 P08684 3/20 0.34
CYP2C9 P11712 2/20 0.34
APP P05067 2/20 0.34
CYP2D6 P10635 1/20 0.33
CYP2C19 P33261 1/20 0.33
FASN P49327 1/20 0.32
PDE3B Q13370 1/20 0.30
PDE3A Q14432 1/20 0.30
PDK2 Q15119 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8959302 0.87 CYP3A4 (0.34) CYP3A4CYP2C9APPCYP2D6CYP2C19
SCHEMBL9018578 0.86 CYP3A4 (0.36) CYP3A4CYP2C9APPCYP2D6CYP2C19
SCHEMBL13263292 0.85 WDR5 (0.31)
SCHEMBL16521133 0.85 CYP3A4 (0.33) CYP3A4CYP2C9APPCYP2D6CYP2C19
SCHEMBL9018752 0.84 CYP3A4 (0.32) CYP3A4CYP2C9APPCYP2D6CYP2C19
SCHEMBL8959329 0.84 CYP3A4 (0.33) CYP3A4CYP2C9APPCYP2D6CYP2C19
SCHEMBL8959306 0.84 FASN (0.36) CYP3A4CYP2C9APPCYP2D6CYP2C19
SCHEMBL8933322 0.83 CYP3A4 (0.36) CYP3A4CYP2C9APPCYP2D6CYP2C19
SCHEMBL8959330 0.82 KDM1A (0.37) CYP3A4CYP2C9APPCYP2D6CYP2C19
SCHEMBL8959307 0.82 FASN (0.33) CYP3A4CYP2C9APPCYP2D6CYP2C19

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2206695-A1 TETRA- OR PENTA-CYCLIC LIQUID CRYSTALLINE COMPOUND HAVING LATERAL FLUORINE, LIQUID CRYSTAL COMPOSITION, AND LIQUID CRYSTAL DISPLAY ELEMENT Chisso Corporation (JP) 2010-07-14 EP disclosed