Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 5/20 | 0.45 |
| ▸ | DPP8 | Q6V1X1 | 3/20 | 0.45 |
| ▸ | DPP7 | Q9UHL4 | 2/20 | 0.45 |
| ▸ | DPP9 | Q86TI2 | 2/20 | 0.45 |
| ▸ | FAP | Q12884 | 1/20 | 0.45 |
| ▸ | FKBP5 | Q13451 | 4/20 | 0.44 |
| ▸ | XIAP | P98170 | 1/20 | 0.42 |
| ▸ | MMP1 | P03956 | 2/20 | 0.41 |
| ▸ | MMP3 | P08254 | 2/20 | 0.41 |
| ▸ | MMP13 | P45452 | 2/20 | 0.41 |
| ▸ | ADAM17 | P78536 | 2/20 | 0.41 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.40 |
| ▸ | FKBP1A | P62942 | 3/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.38 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15386493 | 0.86 | DPP4 (0.46) | DPP4DPP8DPP7DPP9FAP | |
| SCHEMBL24440806 | 0.83 | DPP4 (0.56) | DPP4DPP8DPP7DPP9FAP | |
| SCHEMBL12658501 | 0.83 | DPP4 (0.65) | DPP4DPP8DPP7DPP9FAP | |
| SCHEMBL13399328 | 0.83 | DPP4 (0.65) | DPP4DPP8DPP7DPP9FAP | |
| SCHEMBL15386487 | 0.83 | DPP4 (0.65) | DPP4DPP8DPP7DPP9FAP | |
| SCHEMBL15712090 | 0.82 | DPP4 (0.41) | DPP4DPP8DPP7DPP9FAP | |
| SCHEMBL15028072 | 0.81 | DPP4 (0.58) | DPP4DPP8DPP7DPP9FAP | |
| SCHEMBL13285635 | 0.81 | DPP4 (0.45) | DPP4DPP8DPP7DPP9FAP | |
| SCHEMBL13285822 | 0.80 | DPP4 (0.64) | DPP4DPP8DPP7DPP9FAP | |
| SCHEMBL8246705 | 0.80 | DPP4 (0.43) | DPP4DPP8DPP7DPP9FAP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2204181-A2 | Protease inhibitors | Trustees of Tufts College (US) | 2010-07-07 | — | — | EP | disclosed |