Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5AP | P20292 | 2/20 | 0.38 |
| ▸ | FEN1 | P39748 | 1/20 | 0.38 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | NPC1 | O15118 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | RAB9A | P51151 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2063436 | 0.83 | NR4A2 (0.53) | NR4A2POLBL3MBTL1KDM4ENPC1 | |
| SCHEMBL13269333 | 0.73 | ALOX5AP (0.37) | ALOX5APFEN1KDM4ENPC1ALDH1A1 | |
| SCHEMBL6523534 | 0.72 | SLC2A1 (0.39) | NR4A2KDM4ENPC1ALDH1A1MAPT | |
| SCHEMBL10106660 | 0.70 | NR4A2 (0.46) | NR4A2KDM4ENPC1ALDH1A1LMNA | |
| SCHEMBL2064143 | 0.69 | NR4A2 (0.50) | NR4A2 | |
| SCHEMBL3435404 | 0.69 | NR1H4 (0.36) | KDM4EALDH1A1 | |
| SCHEMBL2064094 | 0.69 | NR4A2 (0.54) | NR4A2NPC1ALDH1A1RAB9A | |
| SCHEMBL2063966 | 0.68 | ALDH1A3 (0.47) | NR4A2POLBKDM4ENPC1ALDH1A1 | |
| SCHEMBL2064754 | 0.66 | FEN1 (0.43) | ALOX5APFEN1 | |
| SCHEMBL16175458 | 0.64 | NR4A2 (0.39) | NR4A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2262803-B1 | POLYSUBSTITUTED DERIVATIVES OF 2-ARYL-6-PHENYL-IMIDAZO[L,2-A] PYRIDINES, AND PREPARATION AND THERAPEUTIC USE THEREOF | SANOFI SA (FR) | 2012-10-17 | — | — | EP | disclosed |