Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPM1B | O75688 | 2/20 | 0.62 |
| ▸ | PPM1A | P35813 | 2/20 | 0.59 |
| ▸ | ALPI | P09923 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.41 |
| ▸ | XIAP | P98170 | 1/20 | 0.41 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.41 |
| ▸ | LTA4H | P09960 | 1/20 | 0.38 |
| ▸ | SLC15A1 | P46059 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | SRR | Q9GZT4 | 2/20 | 0.36 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.36 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.36 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.36 |
| ▸ | LAP3 | P28838 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4315586 | 1.00 | PPM1B (0.62) | PPM1BPPM1AALPIPKMPTGS1 | |
| SCHEMBL5497399 | 1.00 | PPM1B (0.62) | PPM1BPPM1AALPIPKMPTGS1 | |
| SCHEMBL4315591 | 1.00 | PPM1B (0.62) | PPM1BPPM1AALPIPKMPTGS1 | |
| SCHEMBL4315593 | 1.00 | PPM1B (0.62) | PPM1BPPM1AALPIPKMPTGS1 | |
| SCHEMBL27858195 | 0.75 | CYP1A2 (0.50) | PPM1BALPIPKMPTGS1XIAP | |
| SCHEMBL20576648 | 0.73 | PPM1B (0.41) | PPM1BPPM1AALPIPKMPTGS1 | |
| SCHEMBL31106393 | 0.71 | TRPA1 (0.51) | PPM1BALDH1A1CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL1695172 | 0.67 | SLC1A3 (0.49) | ALPIPKMPTGS1XIAPSLC7A5 | |
| SCHEMBL4992286 | 0.67 | ACE (0.42) | PPM1BALPIPKMPTGS1XIAP | |
| SCHEMBL8561050 | 0.66 | ALPI (0.60) | ALPIPKMPTGS1XIAPSLC7A5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2511844-A2 | Advanced drug development and manufacturing | Los Alamos National Security, LLC (US) | 2012-10-17 | — | — | EP | disclosed |