Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA9 | Q16790 | 17/20 | 0.65 |
| ▸ | CA1 | P00915 | 16/20 | 0.65 |
| ▸ | CA2 | P00918 | 16/20 | 0.65 |
| ▸ | CA12 | O43570 | 8/20 | 0.65 |
| ▸ | CA14 | Q9ULX7 | 4/20 | 0.65 |
| ▸ | CA7 | P43166 | 2/20 | 0.63 |
| ▸ | USP2 | O75604 | 1/20 | 0.56 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.56 |
| ▸ | ELF3 | P78545 | 1/20 | 0.55 |
| ▸ | MED23 | Q9ULK4 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14417374 | 1.00 | CA9 (0.65) | CA9CA1CA2CA12CA14 | |
| SCHEMBL17049667 | 0.86 | CA9 (0.74) | CA9CA1CA2CA12CA14 | |
| SCHEMBL15828111 | 0.86 | CA9 (0.83) | CA9CA1CA2CA12CA14 | |
| SCHEMBL14164948 | 0.85 | CA9 (0.72) | CA9CA1CA2CA12CA14 | |
| SCHEMBL13271743 | 0.85 | CA1 (0.52) | CA9CA1CA2CA12CA14 | |
| SCHEMBL2234764 | 0.84 | CA9 (0.83) | CA9CA1CA2CA12CA14 | |
| SCHEMBL14089616 | 0.84 | CA9 (0.73) | CA9CA1CA2CA12CA14 | |
| SCHEMBL20622624 | 0.84 | CA9 (0.75) | CA9CA1CA2CA12CA14 | |
| SCHEMBL12185092 | 0.84 | CA9 (0.73) | CA9CA1CA2CA12CA14 | |
| SCHEMBL12185010 | 0.83 | CA9 (0.70) | CA9CA1CA2CA12CA14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1809340-B1 | STOICHIOMETRICALLY DEFINED DYE-LABELED SUBSTANCES FOR MEASURING THE GLOMERULAR FILTRATION RATE | UNIV RUPRECHT KARLS HEIDELBERG (DE) | 2010-07-07 | — | — | EP | disclosed |