Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA9 | Q16790 | 17/20 | 0.70 |
| ▸ | CA1 | P00915 | 16/20 | 0.70 |
| ▸ | CA2 | P00918 | 16/20 | 0.70 |
| ▸ | CA12 | O43570 | 8/20 | 0.70 |
| ▸ | CA14 | Q9ULX7 | 4/20 | 0.70 |
| ▸ | CA7 | P43166 | 2/20 | 0.70 |
| ▸ | ELF3 | P78545 | 2/20 | 0.60 |
| ▸ | MED23 | Q9ULK4 | 2/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21186772 | 0.93 | CA9 (0.65) | CA9CA1CA2CA12CA14 | |
| SCHEMBL21391543 | 0.91 | CA9 (0.69) | CA9CA1CA2CA12CA14 | |
| SCHEMBL12185092 | 0.91 | CA9 (0.73) | CA9CA1CA2CA12CA14 | |
| SCHEMBL26211588 | 0.91 | CA1 (0.64) | CA9CA1CA2CA12CA14 | |
| SCHEMBL14032096 | 0.90 | CA9 (0.72) | CA9CA1CA2CA12CA14 | |
| SCHEMBL17793595 | 0.90 | CA9 (0.72) | CA9CA1CA2CA12CA14 | |
| SCHEMBL17049667 | 0.90 | CA9 (0.74) | CA9CA1CA2CA12CA14 | |
| SCHEMBL15910186 | 0.90 | CA1 (0.68) | CA9CA1CA2CA12CA14 | |
| SCHEMBL19426705 | 0.89 | CA9 (0.71) | CA9CA1CA2CA12CA14 | |
| SCHEMBL20622624 | 0.89 | CA9 (0.75) | CA9CA1CA2CA12CA14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2975409-A1 | ZANAMIVIR PHOSPHONATE CONGENERS WITH ANTI-INFLUENZA ACTIVITY AND DETERMINING OSELTAMIVIR SUSCEPTIBILITY OF INFLUENZA VIRUSES | Academia Sinica (TW) | 2016-01-20 | — | — | EP | disclosed |
| EP-2568976-B1 | ZANAMIVIR PHOSPHONATE CONGENERS WITH ANTI-INFLUENZA ACTIVITY AND DETERMINING OSELTAMIVIR SUSCEPTIBILITY OF INFLUENZA VIRUSES | ACADEMIA SINICA (TW) | 2015-09-30 | — | — | EP | disclosed |
| WO-2014100615-A1 | CHIMERIC ANTIGEN RECEPTOR-EXPRESSING T CELLS AS ANTI-CANCER THERAPEUTICS | PURDUE RESEARCH FOUNDATION (US) | 2014-06-26 | — | — | WO | disclosed |
| WO-2011143262-A2 | ZANAMIVIR PHOSPHONATE CONGENERS WITH ANTI-INFLUENZA ACTIVITY AND DETERMINING OSELTAMIVIR SUSCEPTIBILITY OF INFLUENZA VIRUSES | SINICA, ACADEMIA (TW) | 2011-11-17 | — | — | WO | disclosed |