Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DGAT1 | O75907 | 20/20 | 0.61 |
| ▸ | SOAT2 | O75908 | 1/20 | 0.52 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13272786 | 0.93 | DGAT1 (0.56) | DGAT1SOAT2SOAT1 | |
| SCHEMBL2447634 | 0.89 | DGAT1 (0.78) | DGAT1SOAT2SOAT1 | |
| SCHEMBL13272784 | 0.83 | DGAT1 (0.62) | DGAT1 | |
| SCHEMBL10296207 | 0.82 | DGAT1 (0.70) | DGAT1SOAT2SOAT1 | |
| SCHEMBL2512473 | 0.80 | GAA (0.53) | DGAT1SOAT2SOAT1 | |
| SCHEMBL2540947 | 0.80 | DGAT1 (0.70) | DGAT1SOAT2SOAT1 | |
| SCHEMBL13273140 | 0.79 | DGAT1 (0.60) | DGAT1 | |
| SCHEMBL13229422 | 0.79 | DGAT1 (0.80) | DGAT1 | |
| SCHEMBL595918 | 0.79 | DGAT1 (0.86) | DGAT1SOAT2SOAT1 | |
| SCHEMBL10296208 | 0.78 | DGAT1 (0.73) | DGAT1SOAT2SOAT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010077861-A1 | INHIBITORS OF DIACYLGLYCEROL ACLYTRANSFERASE | VIA PHARMACEUTICALS, INC (US) | 2010-07-08 | — | — | WO | disclosed |