Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 9/20 | 0.43 |
| ▸ | RAB9A | P51151 | 4/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.41 |
| ▸ | NPC1 | O15118 | 3/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13098830 | 0.87 | ALDH1A1 (0.48) | HRH3SMN1; SMN2NPC1MEN1KMT2A | |
| SCHEMBL13098833 | 0.85 | HRH3 (0.42) | HRH3 | |
| SCHEMBL13098832 | 0.85 | HRH3 (0.42) | HRH3 | |
| SCHEMBL3107287 | 0.84 | HRH3 (0.43) | HRH3 | |
| SCHEMBL3102261 | 0.84 | HRH3 (0.43) | HRH3 | |
| SCHEMBL13273259 | 0.84 | HRH3 (0.43) | HRH3 | |
| SCHEMBL13099117 | 0.84 | HRH3 (0.42) | HRH3S1PR1 | |
| SCHEMBL13099181 | 0.81 | HRH3 (0.40) | HRH3 | |
| SCHEMBL13099102 | 0.81 | HRH3 (0.40) | HRH3 | |
| SCHEMBL13098826 | 0.81 | PIM1 (0.43) | RAB9ASMN1; SMN2NPC1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2204379-A1 | POLYPEPTIDE COMPOUND | Astellas Pharma Inc. (JP) | 2010-07-07 | — | — | EP | disclosed |