Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 2/20 | 0.59 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.56 |
| ▸ | MEN1 | O00255 | 3/20 | 0.56 |
| ▸ | POLB | P06746 | 2/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | SCN2A | Q99250 | 4/20 | 0.37 |
| ▸ | PIM3 | Q86V86 | 1/20 | 0.37 |
| ▸ | HIPK4 | Q8NE63 | 1/20 | 0.37 |
| ▸ | CA9 | Q16790 | 2/20 | 0.36 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.36 |
| ▸ | ACHE | P22303 | 1/20 | 0.36 |
| ▸ | BACE1 | P56817 | 1/20 | 0.36 |
| ▸ | CA12 | O43570 | 1/20 | 0.35 |
| ▸ | CA1 | P00915 | 1/20 | 0.35 |
| ▸ | CA2 | P00918 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20268569 | 0.77 | PGR (0.50) | KMT2AMEN1 | |
| SCHEMBL18320042 | 0.77 | PGR (0.50) | KMT2AMEN1 | |
| SCHEMBL2762197 | 0.76 | GAA (1.00) | GAAMAPK1KMT2AMEN1POLB | |
| SCHEMBL29963500 | 0.76 | GAA (1.00) | GAAMAPK1KMT2AMEN1POLB | |
| SCHEMBL8273542 | 0.74 | KMT2A (0.88) | GAAMAPK1KMT2AMEN1POLB | |
| SCHEMBL5337809 | 0.74 | GAA (0.62) | GAAMAPK1KMT2AMEN1POLB | |
| SCHEMBL13196418 | 0.74 | GAA (0.62) | GAAMAPK1KMT2AMEN1POLB | |
| SCHEMBL5338177 | 0.74 | GAA (0.62) | GAAMAPK1KMT2AMEN1POLB | |
| SCHEMBL5335747 | 0.74 | GAA (0.62) | GAAMAPK1KMT2AMEN1POLB | |
| SCHEMBL2761694 | 0.74 | GAA (0.62) | GAAMAPK1KMT2AMEN1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010077839-A1 | SUBSTITUTED OXINDOL CB2 AGONISTS FOR PAIN TREATMENT | WYETH LLC (FORMERLY KNOWN AS WYETH) (US) | 2010-07-08 | — | — | WO | disclosed |