⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7049537 | 0.97 | PAOX (0.41) | — | |
| SCHEMBL7049229 | 0.92 | — | — | |
| SCHEMBL3023756 | 0.89 | PAOX (0.50) | — | |
| SCHEMBL17291817 | 0.86 | PAOX (0.48) | — | |
| SCHEMBL17291826 | 0.86 | PAOX (0.48) | — | |
| SCHEMBL17291829 | 0.86 | PAOX (0.48) | — | |
| SCHEMBL5611725 | 0.86 | PAOX (0.48) | — | |
| Hydrochloric Acid SCHEMBL3024738 | 0.86 | SMOX (0.52) | — | |
| SCHEMBL17291809 | 0.86 | PAOX (0.48) | — | |
| SCHEMBL17291824 | 0.86 | PAOX (0.48) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 280 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118255746-A | Selective CDK12/13 inhibitors and uses thereof | 南京圣和药业股份有限公司 | 2024-06-28 | — | — | CN | claimed |
| CN-118239963-A | Compounds as eIF4E inhibitors and uses thereof | 南京圣和药业股份有限公司 | 2024-06-25 | — | — | CN | claimed |
| CN-118234705-A | Aspartic acid derivative and application thereof in treatment of liver fibrosis, nonalcoholic hepatitis and other metabolic diseases | 深圳利沃生物医药科技有限公司 | 2024-06-21 | — | — | CN | claimed |
| US-RE49934-E1 | Inhibitors of cellular metabolic processes | SERVIER PHARMACEUTICALS LLC (US) | 2024-04-23 | — | — | US | claimed |
| CN-117659050-A | Quinazoline heterocyclic derivatives as KRAS mutation inhibitors for the treatment of cancer | 深圳福沃药业有限公司 | 2024-03-08 | — | — | CN | claimed |
| WO-2023001045-A1 | EXTERNAL ANTI-INFLAMMATORY COUPLING COMPOUND DRUG, AND PREPARATION METHOD THEREFOR AND USE THEREOF | 上海椿安生物医药科技有限公司 | 2023-01-26 | — | — | WO | claimed |
| CN-110323079-B | High-voltage-resistant anion exchange electrolyte membrane and solid-state battery capacitor thereof | 中国科学院青岛生物能源与过程研究所 | 2021-08-27 | — | — | CN | claimed |
| WO-2021158792-A1 | METHODS OF TREATING AUTOIMMUNE OR INFLAMMATORY DISEASES OR DISORDERS | AGIOS PHARMACEUTICALS, INC. (US) | 2021-08-12 | — | — | WO | claimed |
| WO-2021068755-A1 | COMPOUND HAVING BRD4 INHIBITORY ACTIVITY, PREPARATION METHOD THEREFOR AND USE THEREOF | 上海海和药物研究开发股份有限公司 | 2021-04-15 | — | — | WO | claimed |
| US-10800782-B2 | Inhibitors of cellular metabolic processes | Agios Pharmaceutical, Inc. (US) | 2020-10-13 | — | — | US | claimed |
| CN-1257489-A | Substituted benzopyran derivatives for the treatment of inflammation | SEARLE & CO (US) | 2000-06-21 | — | — | CN | claimed |
| WO-1999047521-A1 | HYPNOTIC β-CARBOLINE DERIVATIVES, PROCESS FOR THEIR PREPARATION AND THEIR USE AS MEDICINAL PRODUCTS | MACEF (FR) | 1999-09-23 | — | — | WO | claimed |
| CN-1190390-A | Nitric oxide synthase inhibitors derived from cyclic amidines | SEARLE & CO (US) | 1998-08-12 | — | — | CN | claimed |
| CN-1189823-A | Cyclic amidino formulations useful as nitric oxide synthase inhibitors | SEARLE & CO (US) | 1998-08-05 | — | — | CN | claimed |
| CN-1087092-A | Novel 7 beta-substituted-4-aza-5 alpha-androstan-3-ones as 5 alpha-reductase inhibitors | MERCK & CO INC (US) | 1994-05-25 | — | — | CN | claimed |
| EP-0246114-B1 | PHOTOCHROMIC SPIROPYRAN COMPOUNDS | GEC-MARCONI LIMITED (GB) | 1992-09-02 | — | — | EP | claimed |
| US-4826977-A | Photochromic spiropyran compounds | THE PLESSEY COMPANY PLC (GB) | 1989-05-02 | — | — | US | claimed |
| CN-87104184-A | PHOTOCHROMIC SPIROPYRAN COMPOUNDS | — | 1988-06-29 | — | — | CN | claimed |
| EP-0246114-A2 | Photochromic spiropyran compounds | GEC-MARCONI LIMITED (GB) | 1987-11-19 | — | — | EP | claimed |
| WO-1980000057-A1 | CLEANING AGENT FOR DENTINE SURFACES | DENTAL THERAPEUTICS AB (SE) | 1980-01-24 | — | — | WO | claimed |