Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A1 | P04798 | 4/20 | 0.64 |
| ▸ | CYP1B1 | Q16678 | 4/20 | 0.64 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.64 |
| ▸ | MAPT | P10636 | 4/20 | 0.57 |
| ▸ | APP | P05067 | 3/20 | 0.57 |
| ▸ | TTR | P02766 | 3/20 | 0.53 |
| ▸ | ALOX5 | P09917 | 3/20 | 0.53 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.53 |
| ▸ | MEN1 | O00255 | 3/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.53 |
| ▸ | NPC1 | O15118 | 2/20 | 0.53 |
| ▸ | ABL1 | P00519 | 2/20 | 0.53 |
| ▸ | ABCB1 | P08183 | 2/20 | 0.53 |
| ▸ | GAA | P10253 | 2/20 | 0.53 |
| ▸ | BCR | P11274 | 2/20 | 0.53 |
| ▸ | NQO2 | P16083 | 2/20 | 0.53 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.53 |
| ▸ | RAB9A | P51151 | 2/20 | 0.53 |
| ▸ | GFER | P55789 | 2/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5492159 | 0.83 | CYP1A1 (0.66) | CYP1A1CYP1B1CYP1A2APPTTR | |
| SCHEMBL5492154 | 0.83 | CYP1A1 (0.66) | CYP1A1CYP1B1CYP1A2APPTTR | |
| SCHEMBL5497383 | 0.82 | NFE2L2 (0.66) | CYP1A1CYP1B1CYP1A2MMP1MMP2 | |
| SCHEMBL5497385 | 0.82 | NFE2L2 (0.66) | CYP1A1CYP1B1CYP1A2MMP1MMP2 | |
| SCHEMBL4700886 | 0.81 | CYP1A1 (0.64) | CYP1A1CYP1B1CYP1A2ABCG2ALDH1A1 | |
| SCHEMBL3211619 | 0.81 | BACE1 (0.74) | CYP1A2MAPTAPPALOX5PTGS2 | |
| SCHEMBL3211604 | 0.81 | BACE1 (0.74) | CYP1A2MAPTAPPALOX5PTGS2 | |
| SCHEMBL19327368 | 0.80 | NFE2L2 (0.73) | CYP1A1CYP1B1CYP1A2MAPTAPP | |
| SCHEMBL633823 | 0.80 | NFE2L2 (0.73) | CYP1A1CYP1B1CYP1A2MAPTAPP | |
| SCHEMBL3474871 | 0.80 | NFE2L2 (0.74) | CYP1A1CYP1B1CYP1A2MAPTAPP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9610258-B2 | Methods of stabilizing the extracellular matrix and compositions therefor | MD MATRIX HEALTH LLC (US) | 2017-04-04 | — | — | US | disclosed |
| US-20160243057-A1 | METHODS OF STABILIZING THE EXTRACELLULAR MATRIX AND COMPOSITIONS THEREFOR | MD MATRIX HEALTH LLC DBA MD MATRIX HEALTH INC (US) | 2016-08-25 | — | — | US | disclosed |
| US-20140193480-A1 | TOPICAL ANTI-INFLAMMATORY COMPOSITIONS AND USES THEREOF | MD MATRIX HEALTH LLC DBA MD MATRIX HEALTH INC. (US) | 2014-07-10 | — | — | US | disclosed |
| WO-2012142511-A2 | ORTHOMOLECULAR COMPOSITIONS AND THEIR USE IN STABILIZING THE EXTRACELLULAR MATRIX | MD MATRIX HEALTH LLC DBA MD MATRIX HEALTH INC (US) | 2012-10-18 | — | — | WO | disclosed |