Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.54 |
| ▸ | MAPT | P10636 | 1/20 | 0.53 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | TYR | P14679 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | SLC28A3 | Q9HAS3 | 3/20 | 0.47 |
| ▸ | LGALS1 | P09382 | 2/20 | 0.45 |
| ▸ | LGALS3 | P17931 | 2/20 | 0.45 |
| ▸ | LGALS9 | O00182 | 1/20 | 0.45 |
| ▸ | LGALS8 | O00214 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | ACHE | P22303 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16285372 | 0.86 | SLC28A3 (0.50) | L3MBTL1MAPTGAATYRSLC28A3 | |
| SCHEMBL2429112 | 0.86 | SLC28A3 (0.50) | L3MBTL1MAPTGAATYRSLC28A3 | |
| SCHEMBL3144958 | 0.86 | SLC28A3 (0.50) | L3MBTL1MAPTGAATYRSLC28A3 | |
| SCHEMBL5199795 | 0.86 | SLC28A3 (0.50) | L3MBTL1MAPTGAATYRSLC28A3 | |
| SCHEMBL17523750 | 0.86 | SLC28A3 (0.50) | L3MBTL1MAPTGAATYRSLC28A3 | |
| SCHEMBL229613 | 0.86 | SLC28A3 (0.50) | L3MBTL1MAPTGAATYRSLC28A3 | |
| SCHEMBL6060841 | 0.86 | SLC28A3 (0.50) | L3MBTL1MAPTGAATYRSLC28A3 | |
| SCHEMBL22047951 | 0.86 | SLC28A3 (0.50) | L3MBTL1MAPTGAATYRSLC28A3 | |
| SCHEMBL22026379 | 0.86 | SLC28A3 (0.50) | L3MBTL1MAPTGAATYRSLC28A3 | |
| SCHEMBL5862474 | 0.86 | SLC28A3 (0.50) | L3MBTL1MAPTGAATYRSLC28A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012142457-A2 | MACROLACTAM COMPOUNDS AND METHODS FOR THE TREATMENT OF MALARIA | THE BROAD INSTITUTE, INC. (US) | 2012-10-18 | — | — | WO | disclosed |