SCHEMBL16285372

SCHEMBL16285372

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nearest known ligand 0.60

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
SLC28A3 Q9HAS3 4/20 0.50
L3MBTL1 Q9Y468 1/20 0.50
MAPT P10636 1/20 0.49
PYGB P11216 1/20 0.47
LGALS8 O00214 1/20 0.45
GAA P10253 1/20 0.45
TYR P14679 1/20 0.45
CD69 Q07108 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2429112 1.00 SLC28A3 (0.50) SLC28A3L3MBTL1MAPTPYGBLGALS8
SCHEMBL19603336 1.00 SLC28A3 (0.50) SLC28A3L3MBTL1MAPTPYGBLGALS8
SCHEMBL229613 1.00 SLC28A3 (0.50) SLC28A3L3MBTL1MAPTPYGBLGALS8
SCHEMBL5862474 1.00 SLC28A3 (0.50) SLC28A3L3MBTL1MAPTPYGBLGALS8
SCHEMBL3144972 1.00 SLC28A3 (0.50) SLC28A3L3MBTL1MAPTPYGBLGALS8
SCHEMBL4703623 1.00 SLC28A3 (0.50) SLC28A3L3MBTL1MAPTPYGBLGALS8
SCHEMBL8361874 1.00 SLC28A3 (0.50) SLC28A3L3MBTL1MAPTPYGBLGALS8
SCHEMBL22026379 1.00 SLC28A3 (0.50) SLC28A3L3MBTL1MAPTPYGBLGALS8
SCHEMBL22047951 1.00 SLC28A3 (0.50) SLC28A3L3MBTL1MAPTPYGBLGALS8
SCHEMBL3144958 1.00 SLC28A3 (0.50) SLC28A3L3MBTL1MAPTPYGBLGALS8

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20140364386-A1 Small Molecule Compounds That Control Plant- and Insect-Pathogenic Nematodes CALIFORNIA INSTITUTE OF TECHNOLOGY (US) 2014-12-11 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20140364386-A1 Small Molecule Compounds That Control Plant- and Insect-Pathogenic Nematodes HNMT, EMG1, API5 SLC28A3 4708/4885L3MBTL1 165/4885MAPT 2689/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.