Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MET | P08581 | 20/20 | 0.62 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13152656 | 0.91 | MET (0.71) | MET | |
| SCHEMBL3095826 | 0.90 | MET (0.62) | MET | |
| SCHEMBL2347766 | 0.90 | MET (0.62) | MET | |
| SCHEMBL2348812 | 0.90 | MET (0.62) | MET | |
| SCHEMBL3079125 | 0.88 | MET (0.63) | MET | |
| SCHEMBL3092584 | 0.87 | MET (0.61) | MET | |
| SCHEMBL3084139 | 0.86 | MET (0.64) | MET | |
| SCHEMBL3095953 | 0.86 | MET (0.57) | MET | |
| SCHEMBL3088599 | 0.85 | MET (0.76) | MET | |
| SCHEMBL2455862 | 0.85 | MET (0.63) | MET |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010072295-A1 | NOVEL POLYMORPHIC FORMS OF 6-(1-METHYL-1H-PYRAZOL-4-YL)-2-{3-[5-(2-MORPHOLIN-4-YL-ETHOXY)-PYRIMIDIN-2-YL]-BENZYL}-2H-PYRIDAZIN-3-ONE DIHYDROGENPHOSPHATE AND PROCESSES OF MANUFACTURING THEREOF | MERCK PATENT GMBH (DE) | 2010-07-01 | — | — | WO | disclosed |