Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR119 | Q8TDV5 | 20/20 | 0.58 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13282087 | 0.80 | GPR119 (0.54) | GPR119CYP2C9 | |
| SCHEMBL4355567 | 0.75 | GPR119 (0.52) | GPR119CYP2C9CYP3A4CYP2C19 | |
| SCHEMBL1128552 | 0.75 | GPR119 (0.52) | GPR119CYP2C9CYP3A4CYP2C19 | |
| SCHEMBL1128505 | 0.75 | GPR119 (0.52) | GPR119CYP2C9CYP3A4CYP2C19 | |
| SCHEMBL13282198 | 0.73 | GPR119 (0.35) | GPR119CYP3A4CYP2C19 | |
| SCHEMBL388432 | 0.73 | GPR119 (0.69) | GPR119CYP2C9CYP3A4CYP2C19 | |
| SCHEMBL13282085 | 0.72 | GPR119 (0.62) | GPR119CYP3A4CYP2C19 | |
| SCHEMBL16281420 | 0.72 | GPR119 (0.64) | GPR119CYP3A4CYP2C19 | |
| SCHEMBL4459757 | 0.71 | GPR119 (0.46) | GPR119CYP2C9CYP3A4CYP2C19 | |
| SCHEMBL4454207 | 0.71 | GPR119 (0.46) | GPR119CYP2C9CYP3A4CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010075273-A1 | BICYCLIC HETEROCYCLE DERIVATIVES AND METHODS OF USE THEREOF | SCHERING CORPORATION (US) | 2010-07-01 | — | — | WO | disclosed |