Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 5/20 | 0.50 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2482395 | 0.86 | PDE10A (0.48) | CNR2PDE10A | |
| SCHEMBL13282736 | 0.77 | — | — | |
| SCHEMBL28813493 | 0.74 | CSF1R (0.49) | CNR2 | |
| SCHEMBL5316181 | 0.70 | CNR2 (0.49) | CNR2 | |
| SCHEMBL2486840 | 0.69 | PDE10A (0.61) | PDE10A | |
| SCHEMBL2484162 | 0.69 | — | — | |
| SCHEMBL2485839 | 0.69 | PDE10A (0.76) | PDE10A | |
| SCHEMBL13282545 | 0.69 | SCN9A (0.47) | — | |
| SCHEMBL392141 | 0.68 | HRH3 (0.56) | — | |
| SCHEMBL13282541 | 0.68 | GRM5 (0.48) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010077992-A1 | AMINOPYRIDINE AND CARBOXYPYRIDINE COMPOUNDS AS PHOSPHODIESTERASE 10 INHIBITORS | AMGEN INC. (US) | 2010-07-08 | — | — | WO | disclosed |