Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 6/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.40 |
| ▸ | EGFR | P00533 | 2/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | KDR | P35968 | 2/20 | 0.39 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.39 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.39 |
| ▸ | AURKA | O14965 | 1/20 | 0.39 |
| ▸ | RPS6KB1 | P23443 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | LCK | P06239 | 1/20 | 0.37 |
| ▸ | CDK4 | P11802 | 1/20 | 0.36 |
| ▸ | CDK6 | Q00534 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5312881 | 0.92 | KDR (0.47) | CNR2EGFRKDRADORA2AADORA3 | |
| SCHEMBL5333722 | 0.91 | KDR (0.46) | CNR2EGFRKDRADORA2AADORA3 | |
| SCHEMBL5309903 | 0.90 | CNR2 (0.43) | CNR2SMN1; SMN2KDRADORA2AADORA3 | |
| SCHEMBL5313312 | 0.88 | KDR (0.51) | LMNAMAPTCHRM4EGFRCYP1A2 | |
| SCHEMBL5310195 | 0.81 | LMNA (0.39) | LMNAMAPTCHRM4EGFRCYP1A2 | |
| SCHEMBL5311324 | 0.81 | TNIK (0.45) | LMNAMAPTEGFRCYP3A4KDR | |
| SCHEMBL5312787 | 0.81 | KDR (0.51) | CHRM4EGFRKDRADORA2AADORA3 | |
| SCHEMBL5311824 | 0.79 | KDR (0.48) | EGFRKDRADORA2AADORA3LCK | |
| SCHEMBL5313618 | 0.78 | TNIK (0.39) | LMNAMAPTCYP1A2CYP3A4CYP2C19 | |
| SCHEMBL5331082 | 0.77 | KDR (0.51) | KDRADORA2AADORA3LCK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007058482-A1 | NOVEL INHIBITORS OF PROTEIN KINASE | LG LIFE SCIENCES, LTD. (KR) | 2007-05-24 | — | — | WO | disclosed |