Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.55 |
| ▸ | RAB9A | P51151 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.49 |
| ▸ | HTT | P42858 | 2/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.48 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 3/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.45 |
| ▸ | DHFR | P00374 | 3/20 | 0.43 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.43 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.43 |
| ▸ | CASR | P41180 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3379725 | 0.93 | NPSR1 (0.57) | NPSR1RAB9AALDH1A1HTTCYP1A2 | |
| SCHEMBL3380657 | 0.88 | NPSR1 (0.58) | NPSR1RAB9AALDH1A1HTTCYP1A2 | |
| SCHEMBL13282992 | 0.85 | NPSR1 (0.45) | NPSR1RAB9AALDH1A1HTTCYP1A2 | |
| SCHEMBL13282879 | 0.82 | ALDH1A1 (0.44) | NPSR1RAB9AALDH1A1HTTCYP1A2 | |
| SCHEMBL3379765 | 0.82 | NPSR1 (0.54) | NPSR1RAB9AALDH1A1HTTCYP1A2 | |
| SCHEMBL3380682 | 0.82 | NPSR1 (0.56) | NPSR1RAB9AALDH1A1HTTCYP1A2 | |
| SCHEMBL13283038 | 0.81 | NPSR1 (0.58) | NPSR1RAB9AALDH1A1HTTCYP1A2 | |
| SCHEMBL13102235 | 0.81 | MEN1 (0.48) | NPSR1RAB9AALDH1A1HTTLMNA | |
| SCHEMBL13282997 | 0.81 | NPSR1 (0.58) | NPSR1RAB9AALDH1A1HTTCYP1A2 | |
| SCHEMBL3378370 | 0.81 | NPSR1 (0.55) | NPSR1RAB9AALDH1A1HTTCYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100190746-A1 | QUINAZOLINONES AS POTASSIUM CHANNEL MODULATORS | ICAGEN, INC. (US) | 2010-07-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100190746-A1 | QUINAZOLINONES AS POTASSIUM CHANNEL MODULATORS | KCNQ1, KCNK17, KCNQ2 | NPSR1 1722/4885RAB9A 560/4885ALDH1A1 2776/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.