SCHEMBL13282958

SCHEMBL13282958

Cc1ccc(-c2nc(-c3cnn(C)c3)nc(-c3ccc(O)c(C)c3O)n2)c(O)c1C

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
USP2 O75604 1/20 0.39
TP53 P04637 1/20 0.39
GAA P10253 1/20 0.39
MAPT P10636 1/20 0.39
ALOX15 P16050 1/20 0.39
TSHR P16473 1/20 0.39
MAPK1 P28482 1/20 0.39
HSD17B10 Q99714 1/20 0.39
TDP1 Q9NUW8 1/20 0.39
ACLY P53396 1/20 0.36
SMARCA2 P51531 1/20 0.36
SMARCA4 P51532 1/20 0.36
CHEK1 O14757 1/20 0.34
GRM2 Q14416 1/20 0.34
LATS1 O95835 1/20 0.34
PRKD3 O94806 2/20 0.33
PRKD1 Q15139 2/20 0.33
PRKD2 Q9BZL6 2/20 0.33
CCNC P24863 1/20 0.33
CDK8 P49336 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30772115 0.75 ESR1 (0.44) USP2TP53GAAMAPTALOX15
SCHEMBL3696821 0.75 ESR1 (0.44) USP2TP53GAAMAPTALOX15
SCHEMBL13030469 0.75 MAPT (0.38) MAPTALOX15TSHRMAPK1HSD17B10
SCHEMBL30772116 0.75 ESR1 (0.44) USP2TP53GAAMAPTALOX15
SCHEMBL19792259 0.72 FGFR1 (0.41) TP53TDP1PIM1
SCHEMBL13271093 0.71 MAPT (0.36) USP2TP53GAAMAPTALOX15
SCHEMBL18633733 0.71 ESR1 (0.41) USP2TP53GAAMAPTALOX15
SCHEMBL12714322 0.70 ESR1 (0.41) USP2TP53GAAMAPTALOX15
SCHEMBL13282975 0.70 MAPT (0.41) USP2TP53GAAMAPTALOX15
SCHEMBL3361268 0.69 MAPT (0.41) USP2TP53GAAMAPTALOX15

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2010081835-A2 BIS-RESORCINYL-TRIAZINE DERIVATIVES AS PROTECTING AGENTS AGAINST UV RADIATION ISDIN, S. A. (ES) 2010-07-22 WO disclosed