Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 10/20 | 0.41 |
| ▸ | GAA | P10253 | 5/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.41 |
| ▸ | USP2 | O75604 | 2/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 8/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.37 |
| ▸ | MEN1 | O00255 | 7/20 | 0.37 |
| ▸ | LMNA | P02545 | 5/20 | 0.37 |
| ▸ | CNR1 | P21554 | 1/20 | 0.37 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.37 |
| ▸ | BCHE | P06276 | 1/20 | 0.32 |
| ▸ | ACHE | P22303 | 1/20 | 0.32 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 4/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3360990 | 0.96 | MAPT (0.43) | MAPTGAATDP1ALOX15TSHR | |
| SCHEMBL13270938 | 0.95 | MAPT (0.34) | MAPTGAATDP1ALOX15TSHR | |
| SCHEMBL13271093 | 0.76 | MAPT (0.36) | MAPTGAATDP1ALOX15TSHR | |
| SCHEMBL3696821 | 0.71 | ESR1 (0.44) | MAPTGAATDP1ALOX15TSHR | |
| SCHEMBL13030469 | 0.71 | MAPT (0.38) | MAPTTDP1ALOX15TSHRMAPK1 | |
| SCHEMBL30772116 | 0.71 | ESR1 (0.44) | MAPTGAATDP1ALOX15TSHR | |
| SCHEMBL30772115 | 0.71 | ESR1 (0.44) | MAPTGAATDP1ALOX15TSHR | |
| SCHEMBL3360860 | 0.70 | MAPT (0.39) | MAPTGAATDP1ALOX15TSHR | |
| SCHEMBL13282958 | 0.70 | USP2 (0.39) | MAPTGAATDP1ALOX15TSHR | |
| SCHEMBL3360311 | 0.69 | KDM4E (0.43) | MAPTGAATDP1TSHRMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010081835-A2 | BIS-RESORCINYL-TRIAZINE DERIVATIVES AS PROTECTING AGENTS AGAINST UV RADIATION | ISDIN, S. A. (ES) | 2010-07-22 | — | — | WO | disclosed |