Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRSS1 | P07477 | 5/20 | 0.68 |
| ▸ | KLK1 | P06870 | 4/20 | 0.68 |
| ▸ | F2 | P00734 | 2/20 | 0.68 |
| ▸ | TMPRSS2 | O15393 | 2/20 | 0.68 |
| ▸ | SLC22A2 | O15244 | 1/20 | 0.68 |
| ▸ | HPN | P05981 | 1/20 | 0.68 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.68 |
| ▸ | CTSL | P07711 | 1/20 | 0.68 |
| ▸ | CNR1 | P21554 | 1/20 | 0.68 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.68 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.68 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.68 |
| ▸ | HGFAC | Q04756 | 1/20 | 0.68 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.68 |
| ▸ | SLC47A2 | Q86VL8 | 1/20 | 0.68 |
| ▸ | SLC47A1 | Q96FL8 | 1/20 | 0.68 |
| ▸ | KLK7 | P49862 | 4/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.45 |
| ▸ | NPC1 | O15118 | 2/20 | 0.45 |
| ▸ | POLB | P06746 | 2/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20008640 | 0.90 | PRSS1 (0.68) | PRSS1KLK1F2TMPRSS2SLC22A2 | |
| Camostat SCHEMBL125269 | 0.90 | PRSS1 (0.68) | PRSS1KLK1F2TMPRSS2SLC22A2 | |
| Camostat SCHEMBL2782237 | 0.89 | PRSS1 (0.67) | PRSS1KLK1F2TMPRSS2SLC22A2 | |
| Camostat SCHEMBL8829828 | 0.88 | PRSS1 (0.66) | PRSS1KLK1F2TMPRSS2SLC22A2 | |
| Camostat SCHEMBL1645380 | 0.87 | PRSS1 (0.64) | PRSS1KLK1F2TMPRSS2SLC22A2 | |
| Camostat SCHEMBL1645520 | 0.86 | PRSS1 (0.63) | PRSS1KLK1F2TMPRSS2SLC22A2 | |
| Camostat SCHEMBL871583 | 0.86 | PRSS1 (0.72) | PRSS1KLK1F2TMPRSS2SLC22A2 | |
| Camostat SCHEMBL23803656 | 0.85 | PRSS1 (0.62) | PRSS1KLK1F2TMPRSS2SLC22A2 | |
| Camostat SCHEMBL1648303 | 0.85 | PRSS1 (0.62) | PRSS1KLK1F2TMPRSS2SLC22A2 | |
| Camostat SCHEMBL1646099 | 0.85 | PRSS1 (0.62) | PRSS1KLK1F2TMPRSS2SLC22A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010078867-A1 | METHOD FOR IMPROVED BIOACTIVATION OF MEDICATIONS | CHRISTIAN-ALBRECHTS-UNIVERSITÄT ZU KIEL (DE) | 2010-07-15 | — | — | WO | disclosed |