Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKT1 | P31749 | 1/20 | 0.38 |
| ▸ | BLM | P54132 | 2/20 | 0.38 |
| ▸ | RECQL | P46063 | 2/20 | 0.38 |
| ▸ | POLB | P06746 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | PARP1 | P09874 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | PKM | P14618 | 2/20 | 0.33 |
| ▸ | F2 | P00734 | 1/20 | 0.33 |
| ▸ | F10 | P00742 | 1/20 | 0.33 |
| ▸ | F12 | P00748 | 1/20 | 0.33 |
| ▸ | F7 | P08709 | 1/20 | 0.33 |
| ▸ | F3 | P13726 | 1/20 | 0.33 |
| ▸ | MAOA | P21397 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22060587 | 0.77 | AKT1 (0.43) | AKT1BLMRECQLPOLBMAPT | |
| SCHEMBL18522308 | 0.77 | AKT1 (0.41) | AKT1BLMRECQLPOLBMAPT | |
| SCHEMBL2553036 | 0.77 | AKT1 (0.41) | AKT1BLMRECQLPOLBMAPT | |
| SCHEMBL11269634 | 0.77 | AKT1 (0.41) | AKT1BLMRECQLPOLBMAPT | |
| SCHEMBL16407768 | 0.73 | RECQL (0.38) | AKT1BLMRECQLPOLBMAPT | |
| SCHEMBL27886109 | 0.73 | AKT1 (0.39) | AKT1BLMRECQLPOLBMAPT | |
| SCHEMBL26782059 | 0.73 | RECQL (0.38) | AKT1BLMRECQLPOLBMAPT | |
| SCHEMBL7690754 | 0.73 | AKT1 (0.48) | AKT1BLMRECQLPOLBMAPT | |
| SCHEMBL24848866 | 0.72 | BLM (0.41) | AKT1BLMRECQLPOLBMAPT | |
| SCHEMBL14792478 | 0.72 | RECQL (0.37) | AKT1BLMRECQLPOLBMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2208722-A1 | PROCESS FOR PRODUCTION OF DISULFONIC ACID COMPOUND, ASYMMETRIC MANNICH CATALYST, PROCESS FOR PRODUCTION OF -AMINOCARBONYL DERIVATIVE, AND NOVEL DISULFONATE SALT | National University Corporation Nagoya University (JP) | 2010-07-21 | — | — | EP | disclosed |