SCHEMBL2553036

SCHEMBL2553036

C=CC=CC(=C)c1ccccc1

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
AKT1 P31749 1/20 0.41
MEN1 O00255 3/20 0.36
KMT2A Q03164 3/20 0.36
TSHR P16473 4/20 0.36
MAPT P10636 4/20 0.36
RECQL P46063 2/20 0.36
TDP1 Q9NUW8 2/20 0.36
POLB P06746 1/20 0.36
CYP3A4 P08684 1/20 0.36
PARP1 P09874 1/20 0.36
CYP2C19 P33261 1/20 0.36
BLM P54132 1/20 0.36
PMP22 Q01453 1/20 0.36
HSD17B10 Q99714 1/20 0.36
L3MBTL1 Q9Y468 1/20 0.36
ALOX15 P16050 1/20 0.34
ALDH1A1 P00352 3/20 0.33
MAOB P27338 3/20 0.33
LMNA P02545 2/20 0.33
MAOA P21397 2/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18522308 1.00 AKT1 (0.41) AKT1MEN1KMT2ATSHRMAPT
SCHEMBL11269634 1.00 AKT1 (0.41) AKT1MEN1KMT2ATSHRMAPT
SCHEMBL27886109 0.91 AKT1 (0.39) AKT1MEN1KMT2ATSHRMAPT
Styrene SCHEMBL2548841 0.90 ALDH1A1 (0.52) AKT1MEN1KMT2ATSHRMAPT
Acrylonitrile SCHEMBL9464615 0.89 ALDH1A1 (0.35) AKT1MEN1KMT2ATSHRMAPT
SCHEMBL9722428 0.80 AKT1 (0.32) AKT1
SCHEMBL14340575 0.80 MAPT (0.46) MEN1KMT2AMAPTRECQLTDP1
SCHEMBL2091250 0.80 AKT1 (0.40) AKT1MEN1KMT2ATSHRMAPT
SCHEMBL2091253 0.80 AKT1 (0.40) AKT1MEN1KMT2ATSHRMAPT
SCHEMBL27952159 0.80 ALDH1A1 (0.41) AKT1MEN1KMT2ATSHRMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 41 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2552352-B1 INTRAOCULAR LENS INSERTION DEVICE ABBOTT MEDICAL OPTICS INC (US) 2018-04-25 EP claimed
US-20160081795-A1 INTRAOCULAR LENS INSERTION DEVICE Johnson & Johnson Surgical Vision, Inc. 2016-03-24 US claimed
US-9198754-B2 Intraocular lens insertion device Abbott Medical Optics Inc. (US) 2015-12-01 US claimed
US-20140188122-A1 INTRAOCULAR LENS INSERTION DEVICE Johnson & Johnson Surgical Vision, Inc. 2014-07-03 US claimed
EP-2552352-A2 INTRAOCULAR LENS INSERTION DEVICE Abbott Medical Optics Inc. (US) 2013-02-06 EP claimed
WO-2011123315-A2 INTRAOCULAR LENS INSERTION DEVICE Abbott Medical Optics Inc. (US) 2011-10-06 WO claimed
EP-3691570-A1 INTRAOCULAR LENS (IOL) INJECTOR AND METHOD OF USE THEREOF AST Products, Inc. (US) 2020-08-12 EP disclosed
EP-2932245-B1 DETECTING COATINGS ON INTRAOCULAR LENS INSERTION DEVICES AND METHODS OF MANUFACTURING THE DEVICES JOHNSON & JOHNSON SURGICAL VISION INC (US) 2020-06-17 EP disclosed
US-10577499-B2 Reinforced polycarbonate composition with improved impact performance SABIC GLOBAL TECHNOLOGIES B.V. (NL) 2020-03-03 US disclosed
CN-110800157-A Multilayer magneto-dielectric material 罗杰斯公司 2020-02-14 CN disclosed
US-10426602-B2 Intraocular lens (IOL) injector and method of use thereof AST PRODUCTS, INC. (US) 2019-10-01 US disclosed
US-10420640-B2 Detecting coatings on intraocular lens insertion devices and methods of manufacturing the devices Johnson & Johnson Surgical Vision, Inc. (US) 2019-09-24 US disclosed
WO-2019070282-A1 INTRAOCULAR LENS (IOL) INJECTOR AND METHOD OF USE THEREOF AST PRODUCTS, INC. (US) 2019-04-11 WO disclosed
WO-2006014012-A2 AROMATIC COMPOUNDS OTSUKA PHARMACEUTICAL CO., LTD. (JP) 2006-02-09 WO disclosed
US-6630535-B1 Exhibit damping over a wide temperature and frequency range; tire tread BRIDGESTONE CORPORATION (JP) 2003-10-07 US disclosed
WO-2002016490-A2 RUBBER COMPOSITIONS AND VULCANIZATES INCLUDING COMB-POLYMERS BRIDGESTONE CORPORATION (JP) 2002-02-28 WO disclosed
EP-0502750-A1 Chewing gun containing compositions for controlled release of flavor bearing substances and process for producing same INTERNATIONAL FLAVORS & FRAGRANCES INC. (US) 1992-09-09 EP disclosed
US-5116627-A Chewing gum containing compositions for controlled release of flavor bearing substances and process for producing same INTERNATIONAL FLAVORS & FRAGRANCES INC. (US) 1992-05-26 US disclosed
EP-0000534-B1 PROCESS FOR THE PREPARATION OF VINYL OXIRANES BAYER AG (DE) 1982-02-03 EP disclosed
EP-0000534-A1 Process for the preparation of vinyl oxiranes BAYER AG (DE) 1979-02-07 EP disclosed