SCHEMBL1328358

SCHEMBL1328358

O=C1CCCN1CCl

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Ammonia Solution, Strong SCHEMBL9320676 0.98
SCHEMBL4341665 0.93
SCHEMBL11469728 0.91 L3MBTL1 (0.56)
SCHEMBL9549487 0.91 L3MBTL1 (0.56)
SCHEMBL11473159 0.91 L3MBTL1 (0.56)
SCHEMBL507643 0.81
Hydrochloric Acid SCHEMBL5475006 0.79 PIK3CD (0.48)
SCHEMBL4278259 0.79 KMT2A (0.59)
SCHEMBL261644 0.79 PIK3CD (0.58)
SCHEMBL2493043 0.78 PIK3CD (0.47)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 139 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5321110-A Thickeners for shampoo, hair conditioners ISP INVESTMENTS INC. (US) 1994-06-14 US claimed
EP-0430963-B1 HYDROLYSIS RESISTANT VINYL LACTAM AMINO ACRYLAMIDE POLYMERS ISP INVESTMENTS INC (US) 1994-01-12 EP claimed
EP-0288515-B1 QUATERNIZED NITROGEN CONTAINING COMPOUNDS ISP INVESTMENTS INC. (US) 1993-05-05 EP claimed
EP-0430963-A4 HYDROLYSIS RESISTANT VINYL LACTAM AMINO ACRYLAMIDE POLYMERS 1991-11-21 EP claimed
EP-0430963-A1 HYDROLYSIS RESISTANT VINYL LACTAM AMINO ACRYLAMIDE POLYMERS. GAF CHEMICALS CORP (US) 1991-06-12 EP claimed
US-5011941-A Reacting N-haloalkyl lactam with oxylated tertiary amine GAF CHEMICALS CORPORATION (US) 1991-04-30 US claimed
WO-1990015797-A2 QUATERNIZED NITROGEN CONTAINING COMPOUNDS GAF CHEMICALS CORPORATION (US) 1990-12-27 WO claimed
EP-0307423-A4 MANUFACTURE OF HALOALKYL LACTAMS 1990-12-05 EP claimed
WO-1990001920-A1 HYDROLYSIS RESISTANT VINYL LACTAM AMINO ACRYLAMIDE POLYMERS GAF CHEMICALS CORPORATION (US) 1990-03-08 WO claimed
EP-0307423-A1 MANUFACTURE OF HALOALKYL LACTAMS GAF CHEMICALS CORPORATION (US) 1989-03-22 EP claimed
WO-1988007039-A1 MANUFACTURE OF HALOALKYL LACTAMS GAF CORPORATION (US) 1988-09-22 WO claimed
US-4216152-A Process for making N-(N'-methylenepyrrolidonyl)-2-substituted anilines GAF CORPORATION (US) 1980-08-05 US claimed
CN-105593331-B Composition for polishing 福吉米株式会社 2019-02-22 CN disclosed
EP-2638036-B1 COMPOUND FOR INCREASING KINASE ACTIVE AND APPLICATION THEREOF BETTA PHARMACEUTICALS CO LTD (CN) 2017-08-16 EP disclosed
US-20170081553-A1 POLISHING COMPOSITION FUJIMI INCORPORATED (JP) 2017-03-23 US disclosed
WO-2016144797-A1 ALPHA 7 NICOTINIC ACETYLCHOLINE RECEPTOR ALLOSTERIC MODULATORS, THEIR DERIVATIVES AND USES THEREOF ALPHARMAGEN, LLC (US) 2016-09-15 WO disclosed
EP-0001333-A1 Clavulanic acid derivatives, their preparation and pharmaceutical compositions containing them BEECHAM GROUP PLC (GB) 1979-04-04 EP disclosed
US-4128558-A FIREPROOFING BAYER AKTIENGESELLSCHAFT (DE) 1978-12-05 US disclosed
US-4081472-A CATALYTIC, FROM A CARBAMATE MITSUI TOATSU CHEMICALS INC. (JA) 1978-03-28 US disclosed
US-3956313-A DYES, ACIDIC CATALYST GAF CORPORATION (US) 1976-05-11 US disclosed