Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.41 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.41 |
| ▸ | IDO1 | P14902 | 1/20 | 0.39 |
| ▸ | TDO2 | P48775 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.37 |
| ▸ | FAAH | O00519 | 1/20 | 0.37 |
| ▸ | CA1 | P00915 | 1/20 | 0.37 |
| ▸ | CA2 | P00918 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.37 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.37 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL482545 | 1.00 | HTT (0.46) | HTTALDH1A1CYP2C19CYP3A4ALOX15 | |
| SCHEMBL30494040 | 1.00 | HTT (0.46) | HTTALDH1A1CYP2C19CYP3A4ALOX15 | |
| SCHEMBL14376099 | 1.00 | HTT (0.46) | HTTALDH1A1CYP2C19CYP3A4ALOX15 | |
| SCHEMBL29609183 | 1.00 | HTT (0.46) | HTTALDH1A1CYP2C19CYP3A4ALOX15 | |
| SCHEMBL286556 | 1.00 | HTT (0.46) | HTTALDH1A1CYP2C19CYP3A4ALOX15 | |
| SCHEMBL5117680 | 0.81 | IDO1 (0.43) | HTTALDH1A1CYP2C19CYP3A4ALOX15 | |
| SCHEMBL11604556 | 0.81 | IDO1 (0.43) | HTTALDH1A1CYP2C19CYP3A4ALOX15 | |
| SCHEMBL5117761 | 0.81 | IDO1 (0.43) | HTTALDH1A1CYP2C19CYP3A4ALOX15 | |
| SCHEMBL3372946 | 0.81 | IDO1 (0.43) | HTTALDH1A1CYP2C19CYP3A4ALOX15 | |
| SCHEMBL3375814 | 0.81 | IDO1 (0.43) | HTTALDH1A1CYP2C19CYP3A4ALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 64 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110002961-B | Method for racemization-free synthesis of chiral alcohol | 三峡大学 | 2022-05-03 | — | — | CN | claimed |
| CN-110002961-B | Method for racemization-free synthesis of chiral alcohol | 三峡大学 | 2022-05-03 | — | — | CN | disclosed |
| US-8664216-B2 | Spiro-5,6-dihydro-4H-2,3,5,10b-tetraaza-benzo[e]azulenes | HOFFMANN-LA ROCHE INC. (US) | 2014-03-04 | — | — | US | disclosed |
| EP-2115153-B1 | NITRILASES, NUCLEIC ACIDS ENCODING THEM AND METHODS FOR MAKING AND USING THEM | BP CORP NORTH AMERICA INC (US) | 2013-06-05 | — | — | EP | disclosed |
| EP-1813613-B1 | NOVEL FUSED IMIDAZOLE DERIVATIVE | MSD KK (JP) | 2012-12-19 | — | — | EP | disclosed |
| EP-2356123-B1 | SPIRO-5,6-DIHYDRO-4H-2,3,5,10B-TETRAAZA-BENZO[E]AZULENES | HOFFMANN LA ROCHE (CH) | 2012-10-03 | — | — | EP | disclosed |
| US-8273890-B2 | Thiophene-imidazopyridines | 4SC AG (DE) | 2012-09-25 | — | — | US | disclosed |
| US-8067607-B2 | Potassium channel inhibitors | MERCK SHARP & DOHME CORP. (US) | 2011-11-29 | — | — | US | disclosed |
| US-8067607-B2 | Potassium channel inhibitors | MERCK SHARP & DOHME CORP. (US) | 2011-11-29 | — | — | US | disclosed |
| US-20110282056-A1 | PROTEIN KINASE INHIBITORS AND USE THEREOF | MERCK PATENT GMBH (DE) | 2011-11-17 | — | — | US | disclosed |
| EP-0709465-A2 | Optical resolution for producing optically active alcohol | The Nisshin Oil Mills, Ltd. (JP) | 1996-05-01 | — | — | EP | disclosed |
| EP-0311329-B1 | Liquid crystal compositions comprising optically active 1-[2-halogen-substituted-phenyl]-ethanols and derivatives thereof | CHISSO CORP (JP) | 1994-05-04 | — | — | EP | disclosed |
| EP-0198440-B1 | PROCESS FOR PREPARING OPTICALLY ACTIVE 2-HALO-1-PHENYL ETHANOL | KANEGAFUCHI KAGAKU KOGYO KABUSHIKI KAISHA (JP) | 1992-08-26 | — | — | EP | disclosed |
| US-5068432-A | Amination and etherification of a halo alcohol and resolution of a racemic mixture | ALDRICH CHEMICAL COMPANY, INC. (US) | 1991-11-26 | — | — | US | disclosed |
| US-4918242-A | Novel optically 1,3-phenoxypropylhalides | ALDRICH CHEMICAL COMPANY, INC. (US) | 1990-04-17 | — | — | US | disclosed |
| US-4916074-A | ENZYMATIC TRANS ESTERIFICATION OF ALCOHOL WITH TRIGLYCERIDES; PSEUDOMONAS-DERIVED ENZYME | CHISSO CORPORATION (JP) | 1990-04-10 | — | — | US | disclosed |
| US-4904409-A | LIQUID CRYSTAL HAS HIGH TWISTABILITY | CHISSO CORPORATION (JP) | 1990-02-27 | — | — | US | disclosed |
| US-4857468-A | BIOSYNTHESIS | KANEGAFUCHI KAGAKU KOGYO KABUSHIKI KAISHA (JP) | 1989-08-15 | — | — | US | disclosed |
| EP-0311329-A2 | Liquid crystal compositions comprising optically active 1-[2-halogen-substituted-phenyl]-ethanols and derivatives thereof | Chisso Corporation (JP) | 1989-04-12 | — | — | EP | disclosed |
| EP-0266217-A2 | Process for producing optically active compounds | CHISSO CORPORATION (JP) | 1988-05-04 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110282056-A1 | PROTEIN KINASE INHIBITORS AND USE THEREOF | MAP3K19, MAP3K20, MAP3K1 | HTT 4752/4885ALDH1A1 3339/4885CYP2C19 1534/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.