Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 1/20 | 0.43 |
| ▸ | TDO2 | P48775 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | CFTR | P13569 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | OPRL1 | P41146 | 2/20 | 0.39 |
| ▸ | SLC18A3 | Q16572 | 1/20 | 0.38 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.36 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.36 |
| ▸ | CA1 | P00915 | 2/20 | 0.36 |
| ▸ | CA2 | P00918 | 2/20 | 0.36 |
| ▸ | FAAH | O00519 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3372946 | 1.00 | IDO1 (0.43) | IDO1TDO2HTTCFTRALDH1A1 | |
| SCHEMBL5117680 | 1.00 | IDO1 (0.43) | IDO1TDO2HTTCFTRALDH1A1 | |
| SCHEMBL3375814 | 1.00 | IDO1 (0.43) | IDO1TDO2HTTCFTRALDH1A1 | |
| SCHEMBL11604556 | 1.00 | IDO1 (0.43) | IDO1TDO2HTTCFTRALDH1A1 | |
| SCHEMBL3551469 | 0.88 | HTT (0.43) | IDO1TDO2HTTCFTRALDH1A1 | |
| SCHEMBL11602065 | 0.88 | IDO1 (0.50) | IDO1TDO2ALDH1A1OPRL1CYP2C19 | |
| SCHEMBL14473089 | 0.86 | IDO1 (0.36) | IDO1TDO2HTTCFTRALDH1A1 | |
| SCHEMBL13068680 | 0.86 | IDO1 (0.36) | IDO1TDO2HTTCFTRALDH1A1 | |
| SCHEMBL8038938 | 0.86 | CFTR (0.46) | IDO1TDO2HTTCFTRALDH1A1 | |
| SCHEMBL3905463 | 0.86 | IDO1 (0.42) | IDO1TDO2HTTCFTRALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080319195-A1 | Enantioselective Preparation of Benzimidazole Derivatives and Their Salts | RATIOPHARM GMBH (DE) | 2008-12-25 | — | — | US | disclosed |
| US-20080319195-A1 | Enantioselective Preparation of Benzimidazole Derivatives and Their Salts | RATIOPHARM GMBH (DE) | 2008-12-25 | — | — | US | disclosed |
| US-20080319195-A1 | Enantioselective Preparation of Benzimidazole Derivatives and Their Salts | RATIOPHARM GMBH (DE) | 2008-12-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080319195-A1 | Enantioselective Preparation of Benzimidazole Derivatives and Their Salts | PPOX, CYP3A4, SLC30A5 | IDO1 732/4885TDO2 292/4885HTT 4139/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.