Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAC1 | P63000 | 3/20 | 0.51 |
| ▸ | CDC42 | P60953 | 2/20 | 0.51 |
| ▸ | MAPT | P10636 | 4/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.47 |
| ▸ | BCHE | P06276 | 2/20 | 0.47 |
| ▸ | HPGD | P15428 | 2/20 | 0.47 |
| ▸ | ACHE | P22303 | 2/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | ATP2A1 | O14983 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | USP2 | O75604 | 1/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.47 |
| ▸ | THRB | P10828 | 1/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10132771 | 0.92 | RAC1 (0.42) | RAC1CDC42MAPTKMT2AALDH1A1 | |
| SCHEMBL13284349 | 0.86 | RAC1 (0.53) | RAC1CDC42MAPTKMT2AALDH1A1 | |
| SCHEMBL10162982 | 0.86 | RAC1 (0.55) | RAC1CDC42MAPTKMT2AALDH1A1 | |
| SCHEMBL10132294 | 0.84 | RAC1 (0.38) | RAC1CDC42MAPTKMT2AALDH1A1 | |
| SCHEMBL10132640 | 0.79 | RAC1 (0.44) | RAC1CDC42MAPTKMT2AALDH1A1 | |
| SCHEMBL13284346 | 0.79 | RAC1 (0.52) | RAC1CDC42MAPTKMT2AALDH1A1 | |
| SCHEMBL13284425 | 0.78 | RAC1 (0.47) | RAC1CDC42MAPTKMT2AALDH1A1 | |
| SCHEMBL10132692 | 0.78 | RAC1 (0.46) | RAC1CDC42MAPTKMT2AALDH1A1 | |
| SCHEMBL10132806 | 0.78 | RAC1 (0.40) | RAC1CDC42MAPTKMT2AALDH1A1 | |
| SCHEMBL10163075 | 0.76 | TUBB4A (0.33) | MAPTKMT2AMEN1TUBB4ATUBB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010083436-A1 | BENZO [C] PHENANTHRIDINES AS ANTIMICROBIAL AGENTS | RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY (US) | 2010-07-22 | — | — | WO | disclosed |