Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.60 |
| ▸ | MAPT | P10636 | 3/20 | 0.60 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.60 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.60 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.60 |
| ▸ | PRKDC | P78527 | 1/20 | 0.60 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.60 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | ERN1 | O75460 | 1/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 3/20 | 0.42 |
| ▸ | HPGD | P15428 | 2/20 | 0.42 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29510934 | 0.84 | ALDH1A1 (0.56) | ALDH1A1MAPTKDM4ECYP3A4ALOX15 | |
| SCHEMBL40798 | 0.84 | ALDH1A1 (0.56) | ALDH1A1MAPTKDM4ECYP3A4ALOX15 | |
| SCHEMBL19331554 | 0.81 | ALDH1A1 (0.77) | ALDH1A1MAPTKDM4ECYP3A4ALOX15 | |
| SCHEMBL2494035 | 0.78 | ALDH1A1 (0.68) | ALDH1A1MAPTKDM4ECYP3A4ALOX15 | |
| SCHEMBL3847699 | 0.78 | ALDH1A1 (0.67) | ALDH1A1MAPTKDM4ECYP3A4ALOX15 | |
| SCHEMBL19361406 | 0.77 | ALDH1A1 (0.46) | ALDH1A1MAPTKDM4ECYP3A4ALOX15 | |
| SCHEMBL25648839 | 0.77 | ALDH1A1 (0.61) | ALDH1A1MAPTKDM4ECYP3A4ALOX15 | |
| SCHEMBL28083185 | 0.76 | ALDH1A1 (0.48) | ALDH1A1MAPTKDM4ECYP3A4ALOX15 | |
| SCHEMBL211200 | 0.76 | ALDH1A1 (1.00) | ALDH1A1MAPTKDM4ECYP3A4ALOX15 | |
| SCHEMBL13946710 | 0.75 | SMN1; SMN2 (0.45) | ALDH1A1MAPTKDM4ECYP3A4ALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100190151-A1 | FLUORESCENTLY LABELED NUCLEOSIDE TRIPHOSPHATES AND ANALOGS THEREOF FOR SEQUENCING NUCLEIC ACIDS | CALIFORNIA INSTITUTE OF TECHNOLOGY | 2010-07-29 | — | — | US | disclosed |