Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | VCP | P55072 | 1/20 | 0.69 |
| ▸ | APP | P05067 | 4/20 | 0.64 |
| ▸ | HSP90AA1 | P07900 | 5/20 | 0.61 |
| ▸ | NPSR1 | Q6W5P4 | 4/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.61 |
| ▸ | MAPT | P10636 | 3/20 | 0.61 |
| ▸ | MEN1 | O00255 | 2/20 | 0.61 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.61 |
| ▸ | HTT | P42858 | 2/20 | 0.49 |
| ▸ | S1PR2 | O95136 | 1/20 | 0.49 |
| ▸ | MITF | O75030 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | NPC1 | O15118 | 2/20 | 0.49 |
| ▸ | RAB9A | P51151 | 2/20 | 0.49 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.49 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.49 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.49 |
| ▸ | MMP2 | P08253 | 1/20 | 0.47 |
| ▸ | MMP9 | P14780 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30114875 | 0.90 | APP (0.75) | VCPAPPHSP90AA1NPSR1ALDH1A1 | |
| SCHEMBL10625119 | 0.90 | VCP (0.81) | VCPAPPHSP90AA1NPSR1ALDH1A1 | |
| SCHEMBL978641 | 0.86 | VCP (0.75) | VCPAPPHSP90AA1NPSR1ALDH1A1 | |
| SCHEMBL2504118 | 0.84 | VCP (0.57) | VCPAPPHSP90AA1NPSR1ALDH1A1 | |
| SCHEMBL13077427 | 0.83 | VCP (0.71) | VCPAPPHSP90AA1NPSR1ALDH1A1 | |
| SCHEMBL28552911 | 0.82 | VCP (0.70) | VCPAPPALDH1A1KMT2ASMN1; SMN2 | |
| SCHEMBL24808421 | 0.81 | VCP (0.74) | VCPAPPHSP90AA1NPSR1ALDH1A1 | |
| SCHEMBL9194059 | 0.81 | VCP (0.69) | VCPAPPHSP90AA1NPSR1ALDH1A1 | |
| SCHEMBL15827958 | 0.81 | VCP (1.00) | VCPAPPHSP90AA1NPSR1ALDH1A1 | |
| SCHEMBL8652597 | 0.81 | VCP (0.69) | VCPAPPHSP90AA1NPSR1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111153923-B | Alkynone derivative and preparation method and application thereof | 广东工业大学 | 2023-07-25 | — | — | CN | disclosed |
| CN-115677739-A | Preparation method of O, O-boron difluoride complex | 华南理工大学 | 2023-02-03 | — | — | CN | disclosed |
| CN-110452270-B | Azacarbene palladium complex crystal, synthesis method thereof and application thereof in preparation of alpha, beta-unsaturated ketone compound | 陕西师范大学 | 2022-02-25 | — | — | CN | disclosed |
| CN-111153923-A | Acetylenic ketone derivative and preparation method and application thereof | 广东工业大学 | 2020-05-15 | — | — | CN | disclosed |
| EP-2373721-B1 | ACETYLENIC AROMATIC POLYETHERKETONE | NEXAM CHEMICAL AB (SE) | 2014-06-25 | — | — | EP | disclosed |
| WO-2010072760-A1 | ACETYLENIC AROMATIC POLYETHERKETONE | NEXAM CHEMICAL AB (SE) | 2010-07-01 | — | — | WO | disclosed |