Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGLN1 | Q9GZT9 | 11/20 | 0.53 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.46 |
| ▸ | FTO | Q9C0B1 | 1/20 | 0.45 |
| ▸ | EGLN3 | Q9H6Z9 | 1/20 | 0.45 |
| ▸ | EGFR | P00533 | 2/20 | 0.44 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.43 |
| ▸ | HTR1A | P08908 | 1/20 | 0.43 |
| ▸ | HTR2A | P28223 | 1/20 | 0.43 |
| ▸ | DRD3 | P35462 | 1/20 | 0.43 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.41 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.41 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.41 |
| ▸ | PTPN7 | P35236 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1208104 | 0.86 | EGLN1 (0.62) | EGLN1KDM4CFTOEGLN3EGFR | |
| SCHEMBL7140246 | 0.78 | EGLN1 (0.58) | EGLN1EGFRUSP30HTR1AHTR2A | |
| SCHEMBL14875993 | 0.76 | EGLN1 (0.57) | EGLN1EGFRUSP30HTR1AHTR2A | |
| SCHEMBL5926434 | 0.75 | EGLN1 (0.67) | EGLN1EGFRHTR1AHTR2ADRD3 | |
| SCHEMBL29746814 | 0.75 | EGLN1 (0.54) | EGLN1KDM4CFTOEGLN3EGFR | |
| SCHEMBL29489052 | 0.75 | EGLN1 (0.54) | EGLN1KDM4CFTOEGLN3EGFR | |
| SCHEMBL12256868 | 0.75 | CYP1A2 (0.47) | EGLN1EGFRHTR1AHTR2ADRD3 | |
| SCHEMBL155043 | 0.75 | EGLN1 (0.54) | EGLN1KDM4CFTOEGLN3EGFR | |
| SCHEMBL4076740 | 0.74 | EGLN1 (0.44) | EGLN1KDM4CFTOEGLN3PTPN7 | |
| SCHEMBL23997538 | 0.73 | EGLN1 (0.76) | EGLN1EGFRUSP30HTR1AHTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010083384-A2 | NON-PEPTIDYL, POTENT, AND SELECTIVE MU OPIOID RECEPTOR ANTAGONISTS | VIRGINIA COMMONWEALTH UNIVERSITY (US) | 2010-07-22 | — | — | WO | disclosed |