Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MET | P08581 | 19/20 | 0.59 |
| ▸ | NQO2 | P16083 | 1/20 | 0.49 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13285273 | 0.89 | MET (0.59) | METNQO2 | |
| SCHEMBL2532298 | 0.88 | MET (0.58) | METNQO2 | |
| SCHEMBL3095671 | 0.85 | MET (0.81) | MET | |
| SCHEMBL12240062 | 0.85 | MET (0.64) | METNQO2 | |
| SCHEMBL13970438 | 0.85 | MET (0.55) | METNQO2 | |
| SCHEMBL12106975 | 0.85 | MET (0.56) | METNQO2 | |
| SCHEMBL29549899 | 0.85 | MET (0.69) | METNQO2 | |
| SCHEMBL1296338 | 0.85 | MET (0.69) | METNQO2 | |
| SCHEMBL14494768 | 0.84 | MET (0.50) | METHDAC1 | |
| SCHEMBL12240064 | 0.84 | MET (0.58) | METNQO2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010072296-A1 | PYRIDAZINONE DERIVATIVES | MERCK PATENT GMBH (DE) | 2010-07-01 | — | — | WO | disclosed |
| WO-2009006959-A1 | PYRIDAZINONE DERIVATES | MERCK PATENT GMBH (DE) | 2009-01-15 | — | — | WO | disclosed |