SCHEMBL132849

SCHEMBL132849

C=CCOc1ccccc1C(=O)c1ccccc1

nearest known ligand 0.63

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
LIG1 P18858 1/20 0.63
DRD2 P14416 1/20 0.52
DRD1 P21728 1/20 0.52
DRD3 P35462 1/20 0.52
ABCB1 P08183 7/20 0.50
TSHR P16473 2/20 0.50
GAA P10253 1/20 0.50
ELANE P08246 1/20 0.49
CYP3A4 P08684 1/20 0.49
KDM4E B2RXH2 1/20 0.48
ADRB2 P07550 1/20 0.47
ADRB1 P08588 1/20 0.47
ADRB3 P13945 1/20 0.47
HPGD P15428 1/20 0.46
MAPK1 P28482 1/20 0.46
HSD17B10 Q99714 1/20 0.46
MEN1 O00255 1/20 0.46
KMT2A Q03164 1/20 0.46
AKR1C3 P42330 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9696302 0.90 LIG1 (0.71) LIG1TSHRGAAELANECYP3A4
SCHEMBL22215906 0.89 LIG1 (0.58) LIG1TSHRGAACYP3A4KDM4E
SCHEMBL6656828 0.89 LIG1 (0.58) LIG1DRD2DRD1DRD3ABCB1
SCHEMBL2470333 0.88 LIG1 (0.54) LIG1DRD2DRD1DRD3TSHR
SCHEMBL11855972 0.88 LIG1 (0.57) LIG1DRD2DRD1DRD3TSHR
SCHEMBL5848870 0.88 LIG1 (0.54) LIG1DRD2DRD1DRD3TSHR
SCHEMBL23748273 0.86 LIG1 (0.51) LIG1DRD2DRD1DRD3TSHR
SCHEMBL29519569 0.85 LIG1 (0.69) LIG1TSHRGAACYP3A4KDM4E
SCHEMBL40310 0.85 LIG1 (0.69) LIG1TSHRGAACYP3A4KDM4E
SCHEMBL23748179 0.84 KDM4E (0.68) LIG1DRD2DRD1DRD3ABCB1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 129 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1859835-A2 Topical agent for dermatological use containing 4-hydroxyphenyl-alpha-D-glucopyranoside PENTAPHARM Ltd. (CH) 2007-11-28 EP claimed
EP-2873704-B1 Refinish coating system and repairing method for automotive resin glazing SHINETSU CHEMICAL CO (JP) 2022-03-23 EP disclosed
US-11225061-B2 Oxygen scavenging films CRYOVAC, LLC (US) 2022-01-18 US disclosed
EP-3302960-B1 OXYGEN SCAVENGING FILMS CRYOVAC LLC (US) 2021-12-08 EP disclosed
US-10801649-B2 Fuel tubings and methods for making and using same SAINT-GOBAIN PERFORMANCE PLASTICS CORPORATION (US) 2020-10-13 US disclosed
CN-105593278-B Process for preparing foams from polymerizable condensation polymers 希悦尔公司 2020-09-01 CN disclosed
EP-3687784-A2 FUEL TUBINGS AND METHODS FOR MAKING AND USING SAME Saint-Gobain Performance Plastics Corporation (US) 2020-08-05 EP disclosed
US-10487189-B2 Method of making a foam SEALED AIR CORPORATION (US) (US) 2019-11-26 US disclosed
US-20190093796-A1 FUEL TUBINGS AND METHODS FOR MAKING AND USING SAME SAINT-GOBAIN PERFORMANCE PLASTICS CORPORATION 2019-03-28 US disclosed
EP-2740776-B2 Coating composition for resins SHINETSU CHEMICAL CO (JP) 2018-12-19 EP disclosed
US-6255248-B1 COPOLYMER OF, AT LEAST, ETHYLENE AND A STRAINED, CYCLIC ALKYLENE, PREFERABLY CYCLOPENTENE; A TRANSITION METAL CATALYST CRYOVAC, INC. 2001-07-03 US disclosed
US-6254803-B1 STABILITY OF LAYER OR FILM; LESS BYPRODUCTS AND/OR EFFLUENTS WHICH CAN IMPART AN UNDESIRED TASTE, COLOR, AND/OR ODOR TO THE PACKAGED PRODUCT CRYOVAC, INC. 2001-07-03 US disclosed
US-6254804-B1 STABILITY OF LAYER OR FILM; LESS BYPRODUCTS AND/OR EFFLUENTS WHICH CAN IMPART AN UNDESIRED TASTE, COLOR, AND/OR ODOR TO THE PACKAGED PRODUCT CRYOVAC, INC. 2001-07-03 US disclosed
WO-2001003521-A1 OXYGEN SCAVENGING COMPOSITION CRYOVAC, INC. (US) 2001-01-18 WO disclosed
EP-1066337-A2 OXYGEN SCAVENGERS WITH REDUCED OXIDATION PRODUCTS FOR USE IN PLASTIC FILMS AND BEVERAGE AND FOOD CONTAINERS CHEVRON PHILLIPS CHEMICAL COMPANY LP (US) 2001-01-10 EP disclosed
WO-1999048963-A2 OXYGEN SCAVENGERS WITH REDUCED OXIDATION PRODUCTS FOR USE IN PLASTIC FILMS AND BEVERAGE AND FOOD CONTAINERS CHEVRON PHILLIPS CHEMICAL COMPANY LP (US) 1999-09-30 WO disclosed
WO-1994028053-A1 POLYDIORGANOSILOXANE AND POLYMER MODIFIED BY THE SAME ALLIEDSIGNAL INC. (US) 1994-12-08 WO disclosed
EP-0088842-B1 ORGANOPOLYSILOXANE PHOTOSENSITIZERS AND METHODS FOR THEIR PREPARATION Toray Silicone Company Limited (JP) 1986-01-02 EP disclosed
US-4467082-A Organopolysiloxane photosensitizers and methods for their preparation DOW CORNING CORPORATION (US) 1984-08-21 US disclosed
EP-0088842-A1 Organopolysiloxane photosensitizers and methods for their preparation Toray Silicone Company Limited (JP) 1983-09-21 EP disclosed