SCHEMBL5848870

SCHEMBL5848870

C=CCOc1cccc(C(=O)c2ccccc2)c1O

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LIG1 P18858 1/20 0.54
MAPK1 P28482 2/20 0.46
HSD17B10 Q99714 2/20 0.46
KDM4E B2RXH2 2/20 0.46
MAPT P10636 1/20 0.46
ALOX15 P16050 1/20 0.46
CYP3A4 P08684 1/20 0.44
TSHR P16473 2/20 0.43
GAA P10253 1/20 0.43
HPGD P15428 1/20 0.42
DRD2 P14416 1/20 0.42
DRD1 P21728 1/20 0.42
DRD3 P35462 1/20 0.42
ALDH1A1 P00352 1/20 0.42
ELANE P08246 1/20 0.41
ADRB2 P07550 1/20 0.41
ADRB1 P08588 1/20 0.41
ADRB3 P13945 1/20 0.41
AKR1C3 P42330 1/20 0.41
MEN1 O00255 2/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL132849 0.88 LIG1 (0.63) LIG1MAPK1HSD17B10KDM4ECYP3A4
SCHEMBL2470333 0.86 LIG1 (0.54) LIG1MAPK1HSD17B10KDM4ECYP3A4
SCHEMBL28543647 0.81 DRD2 (0.44) MAPK1HSD17B10KDM4EMAPTALOX15
SCHEMBL7386575 0.81 RAB9A (0.57) MAPK1HSD17B10KDM4EMAPTALOX15
SCHEMBL3942606 0.81 LIG1 (0.54) LIG1MAPK1HSD17B10KDM4EMAPT
SCHEMBL10419379 0.81 MAPT (0.49) MAPK1HSD17B10KDM4EMAPTALOX15
SCHEMBL30876777 0.80 THRB (0.55) MAPK1HSD17B10KDM4EMAPTALOX15
SCHEMBL317182 0.80 THRB (0.55) MAPK1HSD17B10KDM4EMAPTALOX15
SCHEMBL28328204 0.80 LIG1 (0.48) LIG1MAPK1HSD17B10KDM4EMAPT
SCHEMBL15766097 0.80 CYP3A4 (0.44) LIG1MAPK1HSD17B10KDM4EMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119552298-A Ageing-resistant organic silicon acrylate resin, preparation method and application 东莞市雄驰电子有限公司 2025-03-04 CN disclosed
CN-106471043-B UV-active chromophore functionalized polysiloxanes and copolymers made therefrom 莫门蒂夫性能材料股份有限公司 2021-01-12 CN disclosed
EP-3164446-B1 UV-ACTIVE CHROMOPHORE FUNCTIONALIZED POLYILOXANES AND COPOLYMERS MADE THEREFROM MOMENTIVE PERFORMANCE MAT INC (US) 2019-11-20 EP disclosed
EP-3164446-A1 UV-ACTIVE CHROMOPHORE FUNCTIONALIZED POLYILOXANES AND COPOLYMERS MADE THEREFROM Momentive Performance Materials Inc. (US) 2017-05-10 EP disclosed
US-9562159-B2 UV-active chromophore functionalized polysiloxanes and copolymers made therefrom MOMENTIVE PERFORMANCE MATERIAL INC. (US) 2017-02-07 US disclosed
WO-2016004287-A1 UV-ACTIVE CHROMOPHORE FUNCTIONALIZED POLYILOXANES AND COPOLYMERS MADE THEREFROM MOMENTIVE PERFORMANCE MATERIALS INC. (US) 2016-01-07 WO disclosed
US-20160002412-A1 UV-ACTIVE CHROMOPHORE FUNCTIONALIZED POLYSILOXANES AND COPOLYMERS MADE THEREFROM MOMENTIVE PERFORMANCE MATERIALS INC. 2016-01-07 US disclosed
US-7074853-B2 Photoprotective and lightfastness-enhancing siloxanes XEROX CORPORATION (US) 2006-07-11 US disclosed
US-6861458-B2 Photoprotective and lightfastness-enhancing siloxanes XEROX CORPORATION (US) 2005-03-01 US disclosed
US-20050014951-A1 Photoprotective and lightfastness-enhancing siloxanes XEROX CORPORATION 2005-01-20 US disclosed
US-6803395-B2 POLYSILOXANE HAVING THEREON A HYDROPHILIC MOIETY AND A LIGHTFASTNESS MOIETY XEROX CORPORATION 2004-10-12 US disclosed
US-20030137570-A1 Photoprotective and lightfastness-enhancing siloxanes XEROX CORPORATION 2003-07-24 US disclosed
US-20030133886-A1 Photoprotective and lightfastness-enhancing siloxanes XEROX CORPORATION 2003-07-17 US disclosed
US-6569511-B1 Polysiloxane having a hydrophilic moiety and a lightfastness moiety; ink jet coating XEROX CORPORATION 2003-05-27 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20050014951-A1 Photoprotective and lightfastness-enhancing siloxanes LRRFIP1, LRRC59, MMS19 LIG1 66/4885MAPK1 3963/4885HSD17B10 2316/4885
US-20030133886-A1 Photoprotective and lightfastness-enhancing siloxanes ITGA1, ITGB1, ITGB8 LIG1 245/4885MAPK1 3444/4885HSD17B10 2627/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.