Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PHGDH | O43175 | 1/20 | 0.43 |
| ▸ | P2RX7 | Q99572 | 2/20 | 0.40 |
| ▸ | PTGER3 | P43115 | 1/20 | 0.40 |
| ▸ | PTGER2 | P43116 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | CNR2 | P34972 | 6/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | HDAC6 | Q9UBN7 | 3/20 | 0.37 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.37 |
| ▸ | ITGA5 | P08648 | 1/20 | 0.37 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.37 |
| ▸ | CYP2C8 | P10632 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | ACE | P12821 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13284935 | 0.85 | ESR1 (0.46) | PHGDHP2RX7PTGER3PTGER2TDP1 | |
| SCHEMBL289664 | 0.85 | P2RX7 (0.51) | PHGDHP2RX7PTGER3PTGER2TDP1 | |
| SCHEMBL289579 | 0.85 | P2RX7 (0.51) | PHGDHP2RX7PTGER3PTGER2TDP1 | |
| SCHEMBL630463 | 0.85 | P2RX7 (0.51) | PHGDHP2RX7PTGER3PTGER2TDP1 | |
| SCHEMBL9108668 | 0.84 | KMT2A (0.51) | PHGDHPTGER3PTGER2TDP1CNR2 | |
| SCHEMBL9106845 | 0.84 | TDP1 (0.53) | PHGDHP2RX7PTGER3PTGER2TDP1 | |
| SCHEMBL9106851 | 0.84 | TDP1 (0.53) | PHGDHP2RX7PTGER3PTGER2TDP1 | |
| SCHEMBL22798990 | 0.84 | PHGDH (0.43) | PHGDHP2RX7PTGER3PTGER2TDP1 | |
| SCHEMBL10131497 | 0.84 | PHGDH (0.43) | PHGDHP2RX7PTGER3PTGER2TDP1 | |
| SCHEMBL9108663 | 0.84 | KMT2A (0.51) | PHGDHPTGER3PTGER2TDP1CNR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010077836-A2 | PYRROLIDINE COMPOUNDS WHICH MODULATE THE CB2 RECEPTOR | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2010-07-08 | — | — | WO | disclosed |