Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.47 |
| ▸ | NPC1 | O15118 | 2/20 | 0.47 |
| ▸ | RAB9A | P51151 | 2/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | CA12 | O43570 | 2/20 | 0.45 |
| ▸ | CA1 | P00915 | 2/20 | 0.45 |
| ▸ | CA2 | P00918 | 2/20 | 0.45 |
| ▸ | CA7 | P43166 | 2/20 | 0.45 |
| ▸ | CA9 | Q16790 | 2/20 | 0.45 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.45 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 2/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL912444 | 0.85 | CHEK2 (0.59) | ALDH1A1MEN1KMT2AHSP90AA1KDM4E | |
| SCHEMBL2328573 | 0.85 | KDM4E (0.53) | ALDH1A1MEN1KMT2AHSP90AA1KDM4E | |
| SCHEMBL8318161 | 0.84 | ALDH1A1 (0.50) | ALDH1A1MEN1KMT2AHSP90AA1KDM4E | |
| SCHEMBL1313406 | 0.83 | ALDH1A1 (0.49) | ALDH1A1MEN1KMT2AHSP90AA1KDM4E | |
| SCHEMBL16702899 | 0.83 | ALDH1A1 (0.49) | ALDH1A1MEN1KMT2AHSP90AA1KDM4E | |
| SCHEMBL14598660 | 0.81 | KDM4E (0.48) | ALDH1A1MEN1KMT2AKDM4ENPC1 | |
| SCHEMBL5480400 | 0.79 | KDM4E (0.63) | ALDH1A1MEN1KMT2AHSP90AA1KDM4E | |
| SCHEMBL3514549 | 0.77 | CA12 (0.42) | ALDH1A1MEN1KMT2AHSP90AA1KDM4E | |
| SCHEMBL9592679 | 0.77 | MAPT (0.50) | ALDH1A1MEN1KMT2AHSP90AA1KDM4E | |
| SCHEMBL9591718 | 0.76 | ALDH1A1 (0.54) | ALDH1A1MEN1KMT2AKDM4ENPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010080864-A1 | PIPERIDINE-CONTAINING COMPOUNDS AND USE THEREOF | ARRAY BIOPHARMA INC. (US) | 2010-07-15 | — | — | WO | disclosed |