Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | LCK | P06239 | 5/20 | 0.36 |
| ▸ | GRM6 | O15303 | 1/20 | 0.35 |
| ▸ | CISD2 | Q8N5K1 | 1/20 | 0.34 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1317197 | 0.79 | RXFP1 (0.48) | KMT2AALDH1A1HPGD | |
| SCHEMBL9100005 | 0.73 | GRIN2C (0.55) | KMT2AALDH1A1CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL9408177 | 0.70 | KMT2A (0.39) | CA1CA2LCKKMT2AALDH1A1 | |
| SCHEMBL8055683 | 0.70 | ALDH1A1 (0.60) | CISD2PKMKMT2AALDH1A1CYP1A2 | |
| SCHEMBL3043792 | 0.69 | ATR (0.39) | CA1CA2LCK | |
| SCHEMBL9291459 | 0.69 | KMT2A (0.41) | CA1CA2LCKKMT2AALDH1A1 | |
| SCHEMBL25409964 | 0.69 | LCK (0.41) | CA1CA2LCKKMT2AALDH1A1 | |
| SCHEMBL2521302 | 0.69 | CA1 (0.40) | CA1CA2LCKKMT2A | |
| SCHEMBL18114182 | 0.69 | LCK (0.41) | CA1CA2LCK | |
| SCHEMBL538349 | 0.69 | LCK (0.63) | CA1CA2LCKPKMALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010080864-A1 | PIPERIDINE-CONTAINING COMPOUNDS AND USE THEREOF | ARRAY BIOPHARMA INC. (US) | 2010-07-15 | — | — | WO | disclosed |