Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | CA12 | O43570 | 1/20 | 0.44 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 2/20 | 0.43 |
| ▸ | THRB | P10828 | 1/20 | 0.42 |
| ▸ | KLK5 | Q9Y337 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.40 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13286133 | 1.00 | SMN1; SMN2 (0.46) | SMN1; SMN2MEN1KMT2ACYP2C9CYP2C19 | |
| SCHEMBL13286329 | 1.00 | SMN1; SMN2 (0.46) | SMN1; SMN2MEN1KMT2ACYP2C9CYP2C19 | |
| SCHEMBL17742794 | 1.00 | SMN1; SMN2 (0.46) | SMN1; SMN2MEN1KMT2ACYP2C9CYP2C19 | |
| SCHEMBL247552 | 0.83 | CTSK (0.55) | CA12CA14KLK5TSHRTAS1R3 | |
| SCHEMBL8807250 | 0.83 | CTSK (0.55) | CA12CA14KLK5TSHRTAS1R3 | |
| SCHEMBL536280 | 0.83 | CTSK (0.47) | CA12CA14KLK5 | |
| SCHEMBL536281 | 0.83 | CTSK (0.47) | CA12CA14KLK5 | |
| SCHEMBL1505521 | 0.83 | CTSK (0.55) | CA12CA14KLK5TSHRTAS1R3 | |
| SCHEMBL8252284 | 0.82 | CTSK (0.35) | SMN1; SMN2MEN1KMT2ACYP2C9CYP2C19 | |
| SCHEMBL23260554 | 0.81 | CTSK (0.57) | CA12CA14KLK5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010081731-A2 | DERIVATIVES OF SYRINGOLIN A | Max-Planck-Gesellschaft zur Förderung der Wissenschaften e.V (DE) | 2010-07-22 | — | — | WO | disclosed |