SCHEMBL13286294

SCHEMBL13286294

O=C(CCCc1ccc(I)cc1)NCCCCC(NC(=S)Nc1ccc2c(c1)C(=O)OC21c2ccc(O)cc2Oc2cc(O)ccc21)C(=O)O

nearest known ligand 0.78

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
▸ ALB P02768 4/20 0.78
▸ NAALAD2 Q9Y3Q0 10/20 0.62
▸ FOLH1 Q04609 2/20 0.48
▸ NR1H2 P55055 1/20 0.48
▸ KEAP1 Q14145 1/20 0.46
▸ FTO Q9C0B1 4/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13286293 0.88 ALB (1.00) ALBNAALAD2FTO
SCHEMBL24910527 0.83 NAALAD2 (0.66) ALBNAALAD2FOLH1NR1H2KEAP1
SCHEMBL9881740 0.81 NAALAD2 (0.64) ALBNAALAD2FOLH1FTO
SCHEMBL24910738 0.81 NAALAD2 (0.63) ALBNAALAD2FOLH1NR1H2KEAP1
SCHEMBL22863222 0.80 FTO (0.62) NAALAD2FOLH1FTO
SCHEMBL8699727 0.80 FTO (0.60) ALBNAALAD2FTO
SCHEMBL12946728 0.78 ALB (0.81) ALBNAALAD2FOLH1FTO
SCHEMBL15943022 0.77 FTO (0.61) NAALAD2FTO
SCHEMBL22863319 0.76 NAALAD2 (0.63) NAALAD2NR1H2KEAP1FTO
SCHEMBL25711649 0.76 NAALAD2 (0.60) ALBNAALAD2NR1H2KEAP1FTO

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20100172844-A1 ALBUMIN BINDING MOLECULES AND USES THEREOF PHILOCHEM AG (CH) 2010-07-08 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100172844-A1 ALBUMIN BINDING MOLECULES AND USES THEREOF ALB, FABP1, FABP2 ALB 1/4885NAALAD2 137/4885FOLH1 241/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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