⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4056562 | 0.79 | — | — | |
| SCHEMBL28199911 | 0.79 | — | — | |
| SCHEMBL8176615 | 0.75 | — | — | |
| SCHEMBL6636579 | 0.71 | HPGD (0.38) | — | |
| SCHEMBL27990458 | 0.71 | — | — | |
| SCHEMBL6218786 | 0.70 | HPGD (0.46) | — | |
| SCHEMBL21843292 | 0.70 | — | — | |
| SCHEMBL574514 | 0.70 | — | — | |
| SCHEMBL28126272 | 0.69 | — | — | |
| SCHEMBL6634977 | 0.68 | SIGMAR1 (0.45) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2013204-B1 | 2-AMINOPYRIDINE ANALOGS AS GLUCOKINASE ACTIVATORS | ARRAY BIOPHARMA INC (US) | 2015-02-18 | — | — | EP | disclosed |
| EP-2543667-B1 | A method of preparing 2-aminopyridine analogs as glucokinase activators | ARRAY BIOPHARMA INC (US) | 2015-01-28 | — | — | EP | disclosed |
| US-8883828-B2 | 2-aminopyridine analogs as glucokinase activators | ARRAY BIOPHARMA INC. (US) | 2014-11-11 | — | — | US | disclosed |
| EP-2732002-A1 | OIL EMULSIFICATION AND POLYCYCLIC AROMATIC HYDROCARBON ADSORPTION USING FINE PARTICLES AS DISPERSANTS | Cabot Corporation (US) | 2014-05-21 | — | — | EP | disclosed |
| EP-2543667-A9 | 2-aminopyridine analogs as glucokinase activators | Array Biopharma, Inc. (US) | 2013-08-21 | — | — | EP | disclosed |
| US-20130065901-A1 | 2-AMINOPYRIDINE ANALOGS AS GLUCOKINASE ACTIVATORS | ARRAY BIOPHARMA INC. (US) | 2013-03-14 | — | — | US | disclosed |
| WO-2013009744-A1 | OIL EMULSIFICATION AND POLYCYCLIC AROMATIC HYDROCARBON ADSORPTION USING FINE PARTICLES AS DISPERSANTS | CABOT CORPORATION (US) | 2013-01-17 | — | — | WO | disclosed |
| US-8354540-B2 | 2-aminopyridine analogs as glucokinase activators | ARRAY BIOPHARMA INC. (US) | 2013-01-15 | — | — | US | disclosed |
| US-20110281874-A1 | 2-AMINOPYRIDINE ANALOGS AS GLUCOKINASE ACTIVATORS | ARRAY BIOPHARMA INC. (US) | 2011-11-17 | — | — | US | disclosed |
| US-8022223-B2 | 2-aminopyridine analogs as glucokinase activators | ARRAY BIOPHARMA, INC. (US) | 2011-09-20 | — | — | US | disclosed |
| US-20090156603-A1 | 2-AMINOPYRIDINE ANALOGS AS GLUCOKINASE ACTIVATORS | ARRAY BIOPHARMA INC. (US) | 2009-06-18 | — | — | US | disclosed |
| EP-2013204-A2 | 2-AMINOPYRIDINE ANALOGS AS GLUCOKINASE ACTIVATORS | Array Biopharma, Inc. (US) | 2009-01-14 | — | — | EP | disclosed |
| WO-2007117381-A9 | 2 -AMINOPYRIDINE ANALOGS AS GLUCOKINASE ACTIVATORS | ARRAY BIOPHARMA INC (US) | 2008-03-27 | — | — | WO | disclosed |
| WO-2007117381-A2 | 2 -AMINOPYRIDINE ANALOGS AS GLUCOKINASE ACTIVATORS | ARRAY BIOPHARMA INC. (US) | 2007-10-18 | — | — | WO | disclosed |
| US-20020037485-A1 | Method of preparing ultrathin light-sensitive tabular grain emulsions rich in silver bromide | AGFA HEALTHCARE (BE) | 2002-03-28 | — | — | US | disclosed |
| EP-0970073-A4 | PROCESS FOR PREPARING EPROSARTAN | SMITHKLINE BEECHAM CORP (US) | 2001-01-24 | — | — | EP | disclosed |
| EP-0970073-A1 | PROCESS FOR PREPARING EPROSARTAN | SMITHKLINE BEECHAM CORPORATION (US) | 2000-01-12 | — | — | EP | disclosed |
| WO-1998035963-A1 | PROCESS FOR PREPARING EPROSARTAN | SMITHKLINE BEECHAM CORPORATION (US) | 1998-08-20 | — | — | WO | disclosed |
| EP-0189305-B1 | PEPTIDE DERIVATIVES | ICI AMERICAS INC. (US) | 1992-07-29 | — | — | EP | disclosed |
| EP-0189305-A2 | Peptide derivatives | ICI AMERICAS INC. (US) | 1986-07-30 | — | — | EP | disclosed |