Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4A | O75164 | 12/20 | 0.68 |
| ▸ | KDM4C | Q9H3R0 | 12/20 | 0.68 |
| ▸ | KDM5A | P29375 | 1/20 | 0.68 |
| ▸ | KDM7A | Q6ZMT4 | 1/20 | 0.68 |
| ▸ | PHF8 | Q9UPP1 | 1/20 | 0.68 |
| ▸ | KDM2A | Q9Y2K7 | 1/20 | 0.68 |
| ▸ | TSHR | P16473 | 4/20 | 0.60 |
| ▸ | LMNA | P02545 | 2/20 | 0.60 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.60 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.55 |
| ▸ | PPARG | P37231 | 3/20 | 0.54 |
| ▸ | PPARD | Q03181 | 3/20 | 0.54 |
| ▸ | PPARA | Q07869 | 3/20 | 0.54 |
| ▸ | GPR84 | Q9NQS5 | 2/20 | 0.54 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.54 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.54 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.54 |
| ▸ | SLC22A8 | Q8TCC7 | 1/20 | 0.54 |
| ▸ | TLR2 | O60603 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1176587 | 1.00 | KDM4A (0.68) | KDM4AKDM4CKDM5AKDM7APHF8 | |
| SCHEMBL5530872 | 1.00 | KDM4A (0.68) | KDM4AKDM4CKDM5AKDM7APHF8 | |
| SCHEMBL28020165 | 1.00 | KDM4A (0.68) | KDM4AKDM4CKDM5AKDM7APHF8 | |
| SCHEMBL219327 | 1.00 | KDM4A (0.68) | KDM4AKDM4CKDM5AKDM7APHF8 | |
| SCHEMBL3402761 | 1.00 | KDM4A (0.68) | KDM4AKDM4CKDM5AKDM7APHF8 | |
| SCHEMBL5219324 | 1.00 | KDM4A (0.68) | KDM4AKDM4CKDM5AKDM7APHF8 | |
| SCHEMBL8213501 | 1.00 | KDM4A (0.68) | KDM4AKDM4CKDM5AKDM7APHF8 | |
| SCHEMBL6029256 | 1.00 | KDM4A (0.68) | KDM4AKDM4CKDM5AKDM7APHF8 | |
| Water SCHEMBL11318112 | 0.98 | KDM4A (0.66) | KDM4AKDM4CKDM5AKDM7APHF8 | |
| Hydrochloric Acid SCHEMBL247487 | 0.98 | KDM4A (0.69) | KDM4AKDM4CKDM5AKDM7APHF8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010081731-A2 | DERIVATIVES OF SYRINGOLIN A | Max-Planck-Gesellschaft zur Förderung der Wissenschaften e.V (DE) | 2010-07-22 | — | — | WO | disclosed |