Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4A | O75164 | 12/20 | 0.68 |
| ▸ | KDM4C | Q9H3R0 | 12/20 | 0.68 |
| ▸ | KDM5A | P29375 | 1/20 | 0.68 |
| ▸ | KDM7A | Q6ZMT4 | 1/20 | 0.68 |
| ▸ | PHF8 | Q9UPP1 | 1/20 | 0.68 |
| ▸ | KDM2A | Q9Y2K7 | 1/20 | 0.68 |
| ▸ | TSHR | P16473 | 4/20 | 0.60 |
| ▸ | LMNA | P02545 | 2/20 | 0.60 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.60 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.55 |
| ▸ | PPARG | P37231 | 3/20 | 0.54 |
| ▸ | PPARD | Q03181 | 3/20 | 0.54 |
| ▸ | PPARA | Q07869 | 3/20 | 0.54 |
| ▸ | GPR84 | Q9NQS5 | 2/20 | 0.54 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.54 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.54 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.54 |
| ▸ | SLC22A8 | Q8TCC7 | 1/20 | 0.54 |
| ▸ | TLR2 | O60603 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13286331 | 1.00 | KDM4A (0.68) | KDM4AKDM4CKDM5AKDM7APHF8 | |
| SCHEMBL8213501 | 1.00 | KDM4A (0.68) | KDM4AKDM4CKDM5AKDM7APHF8 | |
| SCHEMBL28020165 | 1.00 | KDM4A (0.68) | KDM4AKDM4CKDM5AKDM7APHF8 | |
| SCHEMBL5530872 | 1.00 | KDM4A (0.68) | KDM4AKDM4CKDM5AKDM7APHF8 | |
| SCHEMBL5219324 | 1.00 | KDM4A (0.68) | KDM4AKDM4CKDM5AKDM7APHF8 | |
| SCHEMBL6029256 | 1.00 | KDM4A (0.68) | KDM4AKDM4CKDM5AKDM7APHF8 | |
| SCHEMBL1176587 | 1.00 | KDM4A (0.68) | KDM4AKDM4CKDM5AKDM7APHF8 | |
| SCHEMBL219327 | 1.00 | KDM4A (0.68) | KDM4AKDM4CKDM5AKDM7APHF8 | |
| Water SCHEMBL11318112 | 0.98 | KDM4A (0.66) | KDM4AKDM4CKDM5AKDM7APHF8 | |
| Bromide SCHEMBL1661208 | 0.98 | KDM4A (0.66) | KDM4AKDM4CKDM5AKDM7APHF8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230320995-A1 | IONIZABLE CATIONIC LIPIDS AND LIPID NANOPARTICLES | CAPSTAN THERAPEUTICS, INC. (US) | 2023-10-12 | — | — | US | disclosed |
| US-8501991-B2 | P53 activating compounds | UNIVERSITY COURT OF THE UNIVERSITY OF DUNDEE (GB) | 2013-08-06 | — | — | US | disclosed |
| EP-2099445-B1 | P53 ACTIVATING BENZOYL UREA AND BENZOYL THIOUREA COMPOUNDS | UNIV DUNDEE (GB) | 2010-11-17 | — | — | EP | disclosed |
| EP-2099445-A2 | P53 ACTIVATING BENZOYL UREA AND BENZOYL THIOUREA COMPOUNDS | University Court of The University of Dundee (GB) | 2009-09-16 | — | — | EP | disclosed |
| WO-2008029096-A2 | P53 ACTIVATING BENZOYL UREA AND BENZOYL THIOUREA COMPOUNDS | UNIVERSITY COURT OF THE UNIVERSITY OF DUNDEE (GB) | 2008-03-13 | — | — | WO | disclosed |
| EP-0988299-A1 | POLYMERISABLE, OPTICALLY ACTIVE DIOXOLANE DIESTERS | Rolic AG (CH) | 2000-03-29 | — | — | EP | disclosed |
| EP-0988283-A2 | PEROXYACIDS | UNILEVER PLC (GB) | 2000-03-29 | — | — | EP | disclosed |
| WO-1998056760-A1 | PEROXYACIDS | UNILEVER PLC (GB) | 1998-12-17 | — | — | WO | disclosed |
| WO-1998055473-A1 | POLYMERISABLE, OPTICALLY ACTIVE DIOXOLANE DIESTERS | ROLIC AG (CH) | 1998-12-10 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230320995-A1 | IONIZABLE CATIONIC LIPIDS AND LIPID NANOPARTICLES | PLTP, LNPEP, PLIN3 | KDM4A 4057/4885KDM4C 4247/4885KDM5A 4704/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.