Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 16/20 | 0.92 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.79 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.79 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.43 |
| ▸ | PREP | P48147 | 3/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18175266 | 1.00 | DPP4 (0.92) | DPP4DPP8DPP9PIK3CAPREP | |
| SCHEMBL13882110 | 1.00 | DPP4 (0.92) | DPP4DPP8DPP9PIK3CAPREP | |
| SCHEMBL2742696 | 1.00 | DPP4 (0.92) | DPP4DPP8DPP9PIK3CAPREP | |
| SCHEMBL1040802 | 0.96 | DPP4 (1.00) | DPP4DPP8DPP9PIK3CAPREP | |
| SCHEMBL2555136 | 0.96 | DPP4 (1.00) | DPP4DPP8DPP9PIK3CAPREP | |
| SCHEMBL646974 | 0.96 | DPP4 (1.00) | DPP4DPP8DPP9PIK3CAPREP | |
| SCHEMBL163502 | 0.96 | DPP4 (1.00) | DPP4DPP8DPP9PIK3CAPREP | |
| SCHEMBL20162036 | 0.96 | DPP4 (1.00) | DPP4DPP8DPP9PIK3CAPREP | |
| SCHEMBL8021363 | 0.94 | DPP4 (0.81) | DPP4DPP8DPP9PIK3CAPREP | |
| SCHEMBL14641775 | 0.94 | DPP4 (0.81) | DPP4DPP8DPP9PIK3CAPREP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2288607-B1 | SULFONAMIDES WITH HETEROCYCLE AND OXADIAZOLONE HEADGROUP, PROCESSES FOR THEIR PREPARATION AND THEIR USE AS PHARMACEUTICALS | SANOFI SA (FR) | 2014-09-24 | — | — | EP | disclosed |
| EP-2288605-B1 | ANNELATED PYRROLIDIN SULFONAMIDES WITH OXADIAZOLONE HEADGROUP, PROCESSES FOR THEIR PREPARATION AND THEIR USE AS PHARMACEUTICALS | SANOFI SA (FR) | 2014-06-25 | — | — | EP | disclosed |
| EP-2288604-B1 | ANNELATED N-HETEROCYCLIC SULFONAMIDES WITH OXADIAZOLONE HEADGROUP, PROCESSES FOR THEIR PREPARATION AND THEIR USE AS PHARMACEUTICALS | SANOFI SA (FR) | 2014-01-08 | — | — | EP | disclosed |
| WO-2009062619-A1 | NEW CRYSTALLINE DIPHENYL ACETIDINONE HYDRATE, PHARMACEUTICAL AGENT CONTAINING SAID COMPOUND AND USE THEREOF | SANOFI-AVENTIS DEUTSCHLAND GMBH (DE) | 2009-05-22 | — | — | WO | disclosed |