Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 14/20 | 0.81 |
| ▸ | DPP8 | Q6V1X1 | 2/20 | 0.73 |
| ▸ | DPP9 | Q86TI2 | 2/20 | 0.73 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.40 |
| ▸ | PREP | P48147 | 4/20 | 0.39 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13746843 | 1.00 | DPP4 (0.81) | DPP4DPP8DPP9PIK3CAPREP | |
| SCHEMBL8027037 | 1.00 | DPP4 (0.81) | DPP4DPP8DPP9PIK3CAPREP | |
| SCHEMBL13550825 | 1.00 | DPP4 (0.81) | DPP4DPP8DPP9PIK3CAPREP | |
| SCHEMBL14641775 | 1.00 | DPP4 (0.81) | DPP4DPP8DPP9PIK3CAPREP | |
| SCHEMBL2742696 | 0.94 | DPP4 (0.92) | DPP4DPP8DPP9PIK3CAPREP | |
| SCHEMBL13287073 | 0.94 | DPP4 (0.92) | DPP4DPP8DPP9PIK3CAPREP | |
| SCHEMBL18175266 | 0.94 | DPP4 (0.92) | DPP4DPP8DPP9PIK3CAPREP | |
| SCHEMBL13882110 | 0.94 | DPP4 (0.92) | DPP4DPP8DPP9PIK3CAPREP | |
| SCHEMBL882339 | 0.92 | DPP4 (0.81) | DPP4DPP8DPP9PIK3CAUSP30 | |
| SCHEMBL8024223 | 0.91 | DPP4 (0.69) | DPP4DPP8DPP9PIK3CA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009097998-A1 | ARYLCHALCOGENO-ARYLALKYL-SUBSTITUTED IMIDAZOLIDINE-2,4-DIONES, METHOD FOR THE PRODUCTION THEREOF, MEDICAMENTS CONTAINING SAID COMPOUNDS AND USE THEREOF | SANOFI-AVENTIS (FR) | 2009-08-13 | — | — | WO | disclosed |