Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TOP1 | P11387 | 8/20 | 0.61 |
| ▸ | CXCR5 | P32302 | 1/20 | 0.58 |
| ▸ | APLNR | P35414 | 1/20 | 0.58 |
| ▸ | CCR6 | P51684 | 1/20 | 0.58 |
| ▸ | SLCO1B3 | Q9NPD5 | 1/20 | 0.56 |
| ▸ | SLCO1B1 | Q9Y6L6 | 1/20 | 0.56 |
| ▸ | PTPN1 | P18031 | 8/20 | 0.55 |
| ▸ | IKBKB | O14920 | 1/20 | 0.50 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.50 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.50 |
| ▸ | RELA | Q04206 | 1/20 | 0.50 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13007183 | 0.91 | PTPN1 (0.68) | TOP1CXCR5APLNRCCR6SLCO1B3 | |
| SCHEMBL13559837 | 0.90 | TOP1 (0.66) | TOP1CXCR5APLNRCCR6SLCO1B3 | |
| SCHEMBL15393756 | 0.89 | TOP1 (0.65) | TOP1CXCR5APLNRCCR6SLCO1B3 | |
| SCHEMBL13867748 | 0.89 | TOP1 (0.65) | TOP1CXCR5APLNRCCR6SLCO1B3 | |
| SCHEMBL13867747 | 0.88 | TOP1 (0.65) | TOP1CXCR5APLNRCCR6SLCO1B3 | |
| SCHEMBL13007191 | 0.88 | PTPN1 (0.70) | TOP1CXCR5APLNRCCR6SLCO1B3 | |
| SCHEMBL12944982 | 0.88 | CXCR5 (0.67) | TOP1CXCR5APLNRCCR6SLCO1B3 | |
| SCHEMBL19360128 | 0.88 | CXCR5 (0.67) | TOP1CXCR5APLNRCCR6SLCO1B3 | |
| SCHEMBL23584144 | 0.87 | CXCR5 (0.61) | TOP1CXCR5APLNRCCR6SLCO1B3 | |
| SCHEMBL15393753 | 0.87 | TOP1 (0.62) | TOP1CXCR5APLNRCCR6SLCO1B3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7727561-B2 | from plants in sapindaceae family, such as Xanthoceras sorbifolia; ovarian, skin, bladder, prostate, leukocytes, and bone cancer cell growth inhiitor | PACIFIC ARROW LIMITED (CN) | 2010-06-01 | — | — | US | disclosed |
| US-7727561-B2 | from plants in sapindaceae family, such as Xanthoceras sorbifolia; ovarian, skin, bladder, prostate, leukocytes, and bone cancer cell growth inhiitor | PACIFIC ARROW LIMITED (CN) | 2010-06-01 | — | — | US | disclosed |